Insulin resistance is a disease characterised by an inability of the body to effectively respond
to insulin in terms of increased glucose uptake. However, in most cases, the response to …

The vascular system controls the delivery of nutrients and hormones to muscle, and a
number of hormones may act to regulate muscle metabolism and contractile performance by …

Insulin enhances the compliance of conduit arteries, relaxes resistance arterioles to
increase tissue blood flow, and dilates precapillary arterioles to expand muscle …

Insulin and exercise have been shown to activate glucose transport at least in part via
different signaling pathways. However, it is unknown whether insulin resistance is …

Insulin has an exercise-like action to increase microvascular perfusion of skeletal muscle
and thereby enhance delivery of hormone and nutrient to the myocytes. With insulin …

Exercise induces an increase in glucose transport in muscle. As the acute increase in
glucose transport reverses, it is replaced by an increase in insulin sensitivity. Interleukin-6 …

Skeletal muscle is an important site for insulin to regulate blood glucose levels. It is
estimated that skeletal muscle is responsible for~ 80% of insulin‐mediated glucose disposal …

Supraphysiological doses of insulin enhance total limb blood flow and recruit capillaries in
skeletal muscle. Whether these processes change in response to physiological …

The mechanisms that mediate the tightly controlled production and clearance of glucose
during muscular work are unclear, and it has been suggested that an unidentified “work …

Aim: The aetiology of the development of type 2 diabetes remains unresolved. In the present
study, we assessed whether an impairment of insulin‐mediated microvascular perfusion …