Peroxisome proliferator-activated receptor (PPAR) α is a nuclear receptor activated by
natural ligands such as fatty acids as well as by synthetic ligands such as fibrates currently …

Peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors
that regulate lipid and lipoprotein metabolism, glucose homeostasis and inflammation. The …

Peroxisome proliferator-activated receptors (PPAR) are ligand-activated transcription factors
which form a subfamily of the nuclear receptor gene family. PPAR activators have effects on …

PPARα is a nuclear receptor that regulates liver and skeletal muscle lipid metabolism as
well as glucose homeostasis. Acting as a molecular sensor of endogenous fatty acids (FAs) …

Atherosclerosis is a chronic inflammatory disease with deposition of excessive cholesterol in
the arterial intima. Peroxisome proliferator-activated receptor α (PPARα) is a nuclear …

Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor
family. After activation by specific ligands, they regulate the transcription of genes involved in …

Peroxisome proliferator-activated receptors (PPARs) belong to the nuclear hormone-
receptor superfamily. Originally cloned in 1990, PPARs were found to be mediators of …

Cardiovascular disease events are the result of functional and structural abnormalities in the
arteries and heart. Atherosclerosis is the main cause and pathological basis of …

Peroxisome proliferator–activated receptors (PPARs) are ligand-activated transcription
factors involved in the transcriptional regulation of key metabolic pathways such as lipid …

Lipid homeostasis and inflammation are key determinants in atherogenesis, exemplified by
the requirement of lipid-laden, foam cell macrophages for atherosclerotic lesion formation …