New perspectives in aqueous humor secretion and in glaucoma: the ciliary body as a multifunctional neuroendocrine gland

M Coca-Prados, J Escribano - Progress in retinal and eye research, 2007 - Elsevier
The discovery in the human ocular ciliary body of glaucoma-associated genes (ie, MYOC,
CYP1B1), neuroendocrine processing enzymes, neuroendocrine peptides, steroid …

[HTML][HTML] Differential gene expression in the human ciliary epithelium

M Coca-Prados, J Escribano, J Ortego - Progress in retinal and eye …, 1999 - Elsevier
The generation of expression and subtractive libraries from the ocular ciliary body and
cultured ciliary epithelial cells has been instrumental in the cloning, identification and …

A major pathway for the regulation of intraocular pressure

M Sears, A Mead - International ophthalmology, 1983 - Springer
There has been a suspicion on the part of many clinicians and research scientists that
intraocular pressure can be regulated by neural and/or humoral influences upon the rate of …

[HTML][HTML] Transport components of net secretion of the aqueous humor and their integrated regulation

MM Civan - Current topics in membranes, 1997 - Elsevier
Publisher Summary This chapter presents an overview of the current consensus concerning
aqueous humor formation and discusses the functional components underlying transport by …

Focus on molecular events in the anterior chamber leading to glaucoma

SC Saccà, A Izzotti - Cellular and Molecular Life Sciences, 2014 - Springer
Primary open-angle glaucoma is a multifactorial disease that affects the retinal ganglion
cells, but currently its therapy is to lower the eye pressure. This indicates a definite …

Basis of chloride transport in ciliary epithelium

CW Do, MM Civan - The Journal of membrane biology, 2004 - Springer
The aqueous humor is formed by the bilayered ciliary epithelium. The pigmented ciliary
epithelium (PE) faces the stroma and the nonpigmented ciliary epithelium (NPE) contacts …

[HTML][HTML] Gene expression and functional annotation of the human ciliary body epithelia

SF Janssen, TGMF Gorgels, K Bossers, JB Ten Brink… - 2012 - journals.plos.org
Purpose The ciliary body (CB) of the human eye consists of the non-pigmented (NPE) and
pigmented (PE) neuro-epithelia. We investigated the gene expression of NPE and PE, to …

Alterations of intracellular calcium in human non-pigmented ciliary epithelial cells of the eye

CH Lee, TD Reisine, MB Wax - Experimental eye research, 1989 - Elsevier
The ciliary epithelium of the eye is thought to be responsible for the active production of
aqueous humor. The role of hormones and neuropeptides in mediating this process is …

Outflow of aqueous humor

E Lütjen-Drecoll, TG B'Ann, B Tian… - Journal of …, 2001 - journals.lww.com
Advances over the past decade in understanding the pathophysiologic features of outflow
abnormalities in glaucoma include structural changes in the trabecular meshwork (TM), the …

Effects of glucocorticoids on the trabecular meshwork: towards a better understanding of glaucoma

RJ Wordinger, AF Clarka - Progress in retinal and eye research, 1999 - Elsevier
Glucocorticoid effects on the human trabecular meshwork can be used as a model system in
which to study glaucomatous damage to the trabecular meshwork. One of the most important …