Background: Juvenile idiopathic arthritis (JIA) consists of a heterogeneous group of
disorders with, for the most part, an unknown immunopathogenesis. Although onset and …

Objectives. With the introduction of high-throughput biomarker measurements, traditional
analysis of these markers is increasingly difficult. Using samples from a diverse group of …

Acute phase proteins, synovial fluid (SF) cellular infiltrates, pro-inflammatory (TNF-α, IL-1α,
IL-6) and Th1 (IL-2) and Th2 (IL-4) derived cytokine levels both in plasma and SF were …

Objective. To examine the usefulness of determining extended serum cytokine profiles in
patients with juvenile rheumatoid arthritis (JRA), for the purpose of improving differential …

Objective To identify biomarkers in the first synovial fluid (SF) aspirate obtained from
children with oligoarticular juvenile idiopathic arthritis (JIA), which could be used to identify …

Objective To determine the pattern of expression of Type 1 and Type 2 cytokines in synovial
tissues and fluids (SF) of patients with different forms of juvenile rheumatoid arthritis (JRA) …

Objective To explore biologic correlates to age at onset in patients with juvenile idiopathic
arthritis (JIA) using peripheral blood mononuclear cell (PBMC) gene expression analysis …

Objective Patients with systemic juvenile idiopathic arthritis (JIA) have arthritis, quotidian
fevers, and other extraarticular features. This disease often remains severe and debilitating …

To assess the serum interleukin (IL)-6 and IL-18 levels in patients with systemic juvenile
idiopathic arthritis (s-JIA) and to identify the clinical features of patient subsets with different …

Objective To identify differences in peripheral blood gene expression between patients with
different subclasses of juvenile idiopathic arthritis (JIA) and healthy controls in a multicenter …