Endocannabinoid signaling has recently been implicated in ethanol-seeking behavior. We
analyzed the expression of endocannabinoid-related genes in key brain regions of reward …

Background The endocannabinoid system has been found to play an important role in
modulating alcohol intake. Inhibition or genetic deletion of fatty acid amide hydrolase (FAAH; …

The endocannabinoid system mediates in the pharmacological actions of ethanol and
genetic studies link endocannabinoid signaling to alcoholism. Drugs activating cannabinoid …

Endocannabinoid signaling plays the important role in regulation of ethanol intake. Fatty
acid amide hydrolase (FAAH) is a key membrane protein for metabolism of …

The present study was undertaken to examine whether genetically predetermined
differences in components of the endocannabinoid system were present in the brain of …

Previous studies have shown that mice lacking cannabinoid (CB1) receptor gene consume
markedly reduced levels of ethanol. Mice lacking the enzyme fatty acid amidohydrolase …

Rationale Several lines of evidence indicate that the endogenous cannabinoid system is
involved in the pharmacological and behavioural effects of alcohol. The mesolimbic …

The current review evaluates the evidence that some of the pharmacological and behavioral
effects of ethanol (EtOH), including EtOH-preferring behavior, may be mediated through the …

Rationale A major clinical concern with the use of cannabinoid receptor 1 (CB1) direct
agonists is that these compounds increase alcohol drinking and drug abuse-related …

Background Anandamide (AEA)-dependent signaling is regulated by the catabolic enzyme
fatty acid amide hydrolase (FAAH). Several lines of evidence have demonstrated that FAAH …