[HTML][HTML] Carotid plaque instability and ischemic symptoms are linked to immaturity of microvessels within plaques
BJ Dunmore, MJ McCarthy, AR Naylor… - Journal of vascular …, 2007 - Elsevier
BACKGROUND: Instability and rupture of carotid atherosclerotic plaques leads to
thromboemboli and ischemic symptoms. Angiogenesis occurs within atherosclerotic …
thromboemboli and ischemic symptoms. Angiogenesis occurs within atherosclerotic …
Association between plaque instability, angiogenesis and symptomatic carotid occlusive disease
R Mofidi, TB Crotty, P McCarthy… - Journal of British …, 2001 - academic.oup.com
Background Angiogenesis is a recognized feature of the atherosclerotic process and has
been described in the context of unstable coronary atherosclerotic lesions. The aim of this …
been described in the context of unstable coronary atherosclerotic lesions. The aim of this …
[HTML][HTML] Angiogenesis and the atherosclerotic carotid plaque: an association between symptomatology and plaque morphology
MJ McCarthy, IM Loftus, MM Thompson, L Jones… - Journal of vascular …, 1999 - Elsevier
Purpose: Symptomatic carotid disease resulting from generation of thromboemboli has been
associated with plaque instability and intraplaque hemorrhage. These features of the lesion …
associated with plaque instability and intraplaque hemorrhage. These features of the lesion …
A pathobiologic link between risk factors profile and morphological markers of carotid instability
A Mauriello, GM Sangiorgi, R Virmani, S Trimarchi… - Atherosclerosis, 2010 - Elsevier
OBJECTIVE: Although cardiovascular risk factors have been strongly linked to carotid intimal-
media thickness, their association with plaque progression towards instability is poorly …
media thickness, their association with plaque progression towards instability is poorly …
Carotid atherosclerotic plaques stabilize after stroke: insights into the natural process of atherosclerotic plaque stabilization
W Peeters, WE Hellings, DPV De Kleijn… - … , and vascular biology, 2009 - Am Heart Assoc
Objective—Rupture of unstable atherosclerotic plaques is the pathological substrate for
acute ischemic events. Underlying cellular and molecular characteristics of plaque rupture …
acute ischemic events. Underlying cellular and molecular characteristics of plaque rupture …
[HTML][HTML] Correlations between clinical variables and gene-expression profiles in carotid plaque instability
A Razuvaev, J Ekstrand, L Folkersen, H Agardh… - European Journal of …, 2011 - Elsevier
OBJECTIVE: Strokes, a major cause of disability, are often caused by embolism from
unstable carotid plaques. The aim of this study was to validate a biobank of human carotid …
unstable carotid plaques. The aim of this study was to validate a biobank of human carotid …
[HTML][HTML] Atherosclerotic plaque rupture and intraplaque hemorrhage do not correlate with symptoms in carotid artery stenosis
J Milei, JC Parodi, M Ferreira, A Barrone… - Journal of vascular …, 2003 - Elsevier
OBJECTIVE: Previously we failed to demonstrate a correlation between plaque type and
symptoms in 165 carotid endarterectomy specimens. The purpose of this study was to …
symptoms in 165 carotid endarterectomy specimens. The purpose of this study was to …
Unstable carotid plaques exhibit raised matrix metalloproteinase-8 activity
Background—The fibrous cap of atherosclerotic plaques is composed predominantly of type
I and III collagen. Unstable carotid plaques are characterized by rupture of their cap, leading …
I and III collagen. Unstable carotid plaques are characterized by rupture of their cap, leading …
The symptomatic carotid plaque
J Golledge, RM Greenhalgh, AH Davies - Stroke, 2000 - Am Heart Assoc
Background—The natural histories of equally severe symptomatic and asymptomatic carotid
stenoses are very different, which suggests dichotomy in plaque behavior. The vascular …
stenoses are very different, which suggests dichotomy in plaque behavior. The vascular …
Differences in lesion severity and cellular composition between in vivo assessed upstream and downstream sides of human symptomatic carotid atherosclerotic …
B Fagerberg, M Ryndel, J Kjelldahl… - Journal of vascular …, 2010 - karger.com
Background: The heterogeneous structure of carotid atherosclerotic plaques may be better
understood if it is related to blood flow variations, influencing gene expression and cellular …
understood if it is related to blood flow variations, influencing gene expression and cellular …