Living organisms have adapted to the daily rotation of the earth and regular changes in the
light environment. Life forms anticipate environmental transitions, adapt their own …

Cardiovascular functions, including blood pressure and vascular functions, show diurnal
oscillation. Circadian variations have been clearly shown in the occurrence of …

The circadian clock regulates many aspects of physiology, including cardiovascular function.
Internal oscillators exist in endothelial, smooth muscle cells, and fibroblasts of the …

Background—Cardiovascular disease is the leading cause of death for both men and
women in the United States and the world. A profound pattern exists in the time of day at …

Both the physiological and pathological functions of cardiovascular organs are closely
related to circadian rhythm, an endogenously driven 24-h cycle. Heart rate, blood pressure …

The circadian system in mammals is a hierarchy of oscillators throughout the organism that
are coordinated by the circadian clock in the hypothalamic suprachiasmatic nucleus …

The master mammalian circadian clock (ie central clock), located in the suprachiasmatic
nucleus of the hypothalamus, orchestrates the synchronization of the daily behavioural and …

The activity of several components of the vascular system appears to be diurnally regulated.
Endothelial cell activation, leukocyte and platelet interactions and lipoprotein metabolism …

It is becoming increasingly clear that the intrinsic properties of both the heart and
vasculature exhibit dramatic oscillations over the course of the day. Diurnal variations in the …

Many aspects of human health and disease display daily rhythmicity. The brain's
suprachiasmic nucleus, which interprets recurring external stimuli, and autonomous …