This groundbreaking volume synthesizes the results of the Virginia Adult Twin Study of
Psychiatric and Substance Use Disorders, which yielded longitudinal data on more than …

Context Studies of gene-environment interplay in the development of psychiatric and
substance use disorders are rapidly accumulating. However, few attempts have been made …

This overview presents selected recent developments in twin studies of adult psychiatric
disorders. Subjects examined include the generalizability of heritability estimates, the impact …

The past 30 years of research on the epidemiology of drug use, drug use disorders, and
related conditions, such as HIV, has provided major insight into these conditions. Drug use …

Background Patterns of comorbidity suggest that the common psychiatric and substance use
syndromes may be divisible into 2 broad groups of internalizing and externalizing disorders …

Intriguing findings on genetic and environmental causation suggest a need to reframe the
etiology of mental disorders. Molecular genetics shows that thousands of common and rare …

This article succinctly reviews research achievements in the fields of psychiatric genetics,
psychosocial influences on mental disorder, and developmental processes. The challenges …

Context While both environmental and genetic factors are important in the etiology of
psychoactive substance use (PSU), we know little of how these influences differ through …

A 406 VOLUME 115| NUMBER 8| August 2007• Environmental Health Perspectives injuries,
and nutritional deficiencies—but also consist of psychosocial conditions that relate to the …

Schizophrenia and other types of psychosis incur suffering, high health care costs and loss
of human potential, due to the combination of early onset and poor response to treatment …