Microarray analysis reveals overexpression of CD163 and HO-1 in symptomatic carotid plaques
Objective—We studied by microarray analysis whether symptomatic and asymptomatic
carotid plaques from the same patient differ in gene expression and whether the same …
carotid plaques from the same patient differ in gene expression and whether the same …
Identification of two genes potentially associated in iron-heme homeostasis in human carotid plaque using microarray analysis
H Ayari, G Bricca - Journal of biosciences, 2013 - Springer
Classic characteristics are poor predictors of the risk of thromboembolism. Thus, better
markers for the carotid atheroma plaque formation and symptom causing are needed. Our …
markers for the carotid atheroma plaque formation and symptom causing are needed. Our …
CD163+ macrophages are associated with a vulnerable plaque phenotype in human carotid plaques
E Bengtsson, K Hultman, A Edsfeldt, A Persson… - Scientific Reports, 2020 - nature.com
Macrophages are a functionally heterogeneous group of immune cells abundant in
atherosclerotic plaques. Macrophages expressing CD163 are associated with intraplaque …
atherosclerotic plaques. Macrophages expressing CD163 are associated with intraplaque …
The nature of iron deposits differs between symptomatic and asymptomatic carotid atherosclerotic plaques
D Kopriva, A Kisheev, D Meena, S Pelle, M Karnitsky… - PLoS …, 2015 - journals.plos.org
Iron within atherosclerotic plaque has been implicated as a catalyst of oxidative stress that
causes progression of plaque, and plaque rupture. Iron is believed to accumulate within …
causes progression of plaque, and plaque rupture. Iron is believed to accumulate within …
Distinctive proteomic profiles among different regions of human carotid plaques in men and women
The heterogeneity of atherosclerotic tissue has limited comprehension in proteomic and
metabolomic analyses. To elucidate the functional implications and differences between …
metabolomic analyses. To elucidate the functional implications and differences between …
Gene expression and 18FDG uptake in atherosclerotic carotid plaques
SF Pedersen, M Graebe, AMF Hag… - Nuclear medicine …, 2010 - journals.lww.com
Purpose Metabolic assessment of vascular inflammation by 2-[18 F] fluoro-2-deoxy-D-
glucose positron emission tomography (FDG)-PET is a promising new approach for the …
glucose positron emission tomography (FDG)-PET is a promising new approach for the …
Gene expression differences between stroke-associated and asymptomatic carotid plaques
Atherosclerotic carotid stenosis is an important risk factor for stroke. Carotid plaques (CPs)
causing stroke may present a distinct type of molecular pathology compared with transient …
causing stroke may present a distinct type of molecular pathology compared with transient …
[HTML][HTML] Molecular pathology in vulnerable carotid plaques: correlation with [18]-fluorodeoxyglucose positron emission tomography (FDG-PET)
OBJECTIVES: Atherosclerosis is recognised as an inflammatory disease, and new
diagnostic tools are warranted to evaluate plaque inflammatory activity and risk of …
diagnostic tools are warranted to evaluate plaque inflammatory activity and risk of …
Consistent differences in protein distribution along the longitudinal axis in symptomatic carotid atherosclerotic plaques
Identifying proteins associated with a complicated atherosclerotic plaque phenotype would
provide potential biomarkers for detection of patients at elevated risk for clinically overt …
provide potential biomarkers for detection of patients at elevated risk for clinically overt …
Elevated levels of endothelial-derived microparticles and serum CXCL9 and SCGF-β are associated with unstable asymptomatic carotid plaques.
A Schiro, FL Wilkinson, R Weston, JV Smyth… - Scientific reports, 2015 - nature.com
Endothelial microparticles (EMPs) are released from dysfunctional endothelial cells. We
hypothesised that patients with unstable carotid plaque have higher levels of circulating …
hypothesised that patients with unstable carotid plaque have higher levels of circulating …