Objective—We studied by microarray analysis whether symptomatic and asymptomatic
carotid plaques from the same patient differ in gene expression and whether the same …

Classic characteristics are poor predictors of the risk of thromboembolism. Thus, better
markers for the carotid atheroma plaque formation and symptom causing are needed. Our …

Macrophages are a functionally heterogeneous group of immune cells abundant in
atherosclerotic plaques. Macrophages expressing CD163 are associated with intraplaque …

Iron within atherosclerotic plaque has been implicated as a catalyst of oxidative stress that
causes progression of plaque, and plaque rupture. Iron is believed to accumulate within …

The heterogeneity of atherosclerotic tissue has limited comprehension in proteomic and
metabolomic analyses. To elucidate the functional implications and differences between …

Purpose Metabolic assessment of vascular inflammation by 2-[18 F] fluoro-2-deoxy-D-
glucose positron emission tomography (FDG)-PET is a promising new approach for the …

Atherosclerotic carotid stenosis is an important risk factor for stroke. Carotid plaques (CPs)
causing stroke may present a distinct type of molecular pathology compared with transient …

OBJECTIVES: Atherosclerosis is recognised as an inflammatory disease, and new
diagnostic tools are warranted to evaluate plaque inflammatory activity and risk of …

Identifying proteins associated with a complicated atherosclerotic plaque phenotype would
provide potential biomarkers for detection of patients at elevated risk for clinically overt …

Endothelial microparticles (EMPs) are released from dysfunctional endothelial cells. We
hypothesised that patients with unstable carotid plaque have higher levels of circulating …