[PDF][PDF] Purified Mouse Anti-Human DNA-PK

BD Pharmingen - ulab360.com
The ability of mammalian cells to detect and repair DNA damage is essential in maintaining
the structural integrity of their genes. Cells have evolved a number of repair pathways in …

Cryo-EM structure of the DNA-PK holoenzyme

H Sharif, Y Li, Y Dong, L Dong… - Proceedings of the …, 2017 - National Acad Sciences
DNA-dependent protein kinase (DNA-PK) is a large protein complex central to the
nonhomologous end joining (NHEJ) DNA-repair pathway. It comprises the DNA-PK catalytic …

Purification of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) from HeLa cells

L Lee, Y Yu, SP Lees-Miller - DNA Damage Responses: Methods and …, 2022 - Springer
With a predicted molecular mass of 469 kDa, expression of recombinant DNA-dependent
protein kinase catalytic subunit (DNA-PKcs) is challenging. However, DNA-PKcs is relatively …

Gene for the catalytic subunit of the human DNA-activated protein kinase maps to the site of the XRCC7 gene on chromosome 8.

JD Sipley, JC Menninger, KO Hartley… - Proceedings of the …, 1995 - National Acad Sciences
The DNA-activated serine/threonine protein kinase (DNA-PK) is composed of a large
(approximately 460 kDa) catalytic polypeptide (DNA-PKcs) and Ku, a heterodimeric DNA …

XRCC4: a candidate for in vivo substrate of DNA-PK

Y Matsumoto, Y Hosoi, N Suzuki, M Tomita - 2003 - osti.gov
Ionizing radiation can induce various types of DNA damages and, among them, double-
strand break (DSB) is considered the most critical lesion. DNA-PK is activated in vitro upon …

[图书][B] Identification and characterization of proteins that interact with the human DNA-dependent protein kinase(DNA-PK).

NSY Ting - 1999 - library-archives.canada.ca
One of the key proteins required during cellular responses to DNA damage is the DNA
dependent protein kinase (DNA-PK). DNA-PK is a serine/threonine protein kinase …

More than just strand breaks: the recognition of structural DNA discontinuities by DNA‐dependent protein kinase catalytic subunit

R Dip, H Naegeli - The FASEB journal, 2005 - Wiley Online Library
The DNA‐dependent protein kinase (DNA‐PK) is a trimeric factor originally identified as an
enzyme that becomes activated upon incubation with DNA. Genetic defects in either the …

Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase

P Douglas, GP Sapkota, N Morrice, Y Yu… - Biochemical …, 2002 - portlandpress.com
The DNA-dependent protein kinase (DNA-PK) is required for the repair of DNA double-
strand breaks (DSBs), such as those caused by ionizing radiation and other DNA-damaging …

Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase

A Goodarzi - sussex.figshare.com
The DNA-dependent protein kinase (DNA-PK) is required for the repair of DNA double-
strand breaks (DSBs), such as those caused by ionizing radiation and other DNA-damaging …

[HTML][HTML] DNA-dependent protein kinase catalytic subunit (DNA-PKcs): beyond the DNA double-strand break repair

YR Lee, GS Kang, T Oh, HJ Jo, HJ Park, GO Ahn - Molecules and cells, 2023 - Elsevier
DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a member of the
phosphatidylinositol 3-kinase-related kinase family is a well-known player in repairing DNA …