Until recently, innate immunity was regarded as a relatively nonspecific system designed to
engulf and destroy pathogens. However, new studies show that the innate immune system is …

Apoptotic effects of potential anti-cancer agents (GSL-glycosphingolipid biosynthesis
inhibitor L-PPMP, DNA biosynthesis inhibitor cis-Platin, disialosylgangliosides GD3 and …

The mammalian orthoreoviruses (called simply reoviruses) are the type species of the
Orthoreovirus genus, which also contains viruses that infect birds and reptiles. The …

NF-kB is a ubiquitous transcription factor involved in the regulation of innate immunity,
cellular survival, proliferation, as well as differentiation. Its deregulation is associated with …

Innate immunity is the first line of defense mounted by the host against the pathogens. Innate
immune responses are initiated at receptors that get activated upon pathogen recognition to …

The inducible transcription factor NF-kappaB regulates a wide variety of target genes and
plays a key role in many biological processes. While all NF-kappaB activation pathways …

Nuclear factor (NF)‐κB activating signals, which are discussed in this chapter, induce
phosphorylation of I κB proteins, leading to their ubiquitination and proteasome‐mediated …

The Paramyxoviridae family includes enveloped, negative‐sense, single‐stranded (ss) RNA
viruses, that are major and ubiquitous disease‐causing pathogens of humans and animals …

B virus (Cercopithecine herpesvirus 1) is an alphaherpesvirus indigenous to macaque
monkeys and is closely related to herpes simplex virus type 1 (HSV-1). Disease caused by B …

Nuclear factor-κB (NF-κB) transcription factors regulate B cell development and survival.
However, whether they also have a role during early steps of B cell differentiation is largely …