Autologous transplantation of bone marrow–derived endothelial progenitor cells attenuates monocrotaline-induced pulmonary arterial hypertension in rats
HK Yip, LT Chang, CK Sun, JJ Sheu… - Critical care …, 2008 - journals.lww.com
Objectives: Bone marrow–derived endothelial progenitor cells have been shown to circulate
to damaged vascular endothelium and differentiate into mature endothelial cells. This study …
to damaged vascular endothelium and differentiate into mature endothelial cells. This study …
The ischemic cascade and mediators of ischemic injury
Publisher Summary schemic stroke is caused by a transient or permanent reduction of blood
flow restricted to the territory of a cerebral artery by embolic or thrombotic occlusion …
flow restricted to the territory of a cerebral artery by embolic or thrombotic occlusion …
[HTML][HTML] Central nervous system therapy for lysosomal storage disorders
GM Enns, SL Huhn - Neurosurgical Focus, 2008 - thejns.org
✓ Most lysosomal storage disorders are characterized by progressive central nervous
system impairment, with or without systemic involvement. Affected individuals have an array …
system impairment, with or without systemic involvement. Affected individuals have an array …
Minocycline reduces engraftment and activation of bone marrow‐derived cells but sustains their phagocytic activity in a mouse model of Alzheimer's disease
TM Malm, J Magga, GF Kuh, T Vatanen, M Koistinaho… - Glia, 2008 - Wiley Online Library
Bone marrow (BM)‐derived monocytes contribute to the development of microglial reaction
around β‐amyloid (Aβ) plaques in Alzheimer's disease (AD) and possibly clear Aβ …
around β‐amyloid (Aβ) plaques in Alzheimer's disease (AD) and possibly clear Aβ …
Methamphetamine‐induced neurotoxicity and microglial activation are not mediated by fractalkine receptor signaling
DM Thomas, DM Francescutti‐Verbeem… - Journal of …, 2008 - Wiley Online Library
Methamphetamine (METH) damages dopamine (DA) nerve endings by a process that has
been linked to microglial activation but the signaling pathways that mediate this response …
been linked to microglial activation but the signaling pathways that mediate this response …
Genetic and cellular therapies for cerebral infarction
O Szentirmai, BS Carter - Neurosurgery, 2008 - journals.lww.com
NEUROSURGEONS, WORKING AS surgical scientists, can have a prominent role in
developing and implementing genetic and cellular therapies for cerebral ischemia. The …
developing and implementing genetic and cellular therapies for cerebral ischemia. The …
Cerebral and peripheral amyloid phagocytes—an old liaison with a new twist
M Jucker, FL Heppner - Neuron, 2008 - cell.com
In this month's issue of Nature Medicine, Town et al. suggest that peripheral macrophages
invading the brain reduce cerebral amyloidosis and thus may play a key role in the …
invading the brain reduce cerebral amyloidosis and thus may play a key role in the …
Inducible nitric oxide synthase does not mediate brain damage after transient focal cerebral ischemia in mice
H Prüss, K Prass, L Ghaeni… - Journal of Cerebral …, 2008 - journals.sagepub.com
Nitric oxide produced by the inducible nitric oxide synthase (iNOS) is believed to participate
in the pathogenic events after cerebral ischemia. In this study, we examined the expression …
in the pathogenic events after cerebral ischemia. In this study, we examined the expression …
Hypothalamic proline-rich polypeptide enhances bone marrow colony-forming cell proliferation and stromal progenitor cell differentiation
AA Galoyan, LI Korochkin, EJ Rybalkina… - Cell …, 2008 - journals.sagepub.com
The AGAPEPAEPAQPGVY proline-rich peptide (PRP-1) was isolated from neurosecretory
granules of the bovine neurohypophysis; it is produced by N. supraopticus and N …
granules of the bovine neurohypophysis; it is produced by N. supraopticus and N …
Long-term engraftment of systemically transplanted, gene-modified bone marrow-derived cells in the adult mouse retina
C Boettcher, E Ulbricht, D Helmlinger… - British journal of …, 2008 - bjo.bmj.com
Aims: To provide evidence for a novel route of gene administration to normal and diseased
retinas, we performed systemic transplantation of genetically engineered bone marrow …
retinas, we performed systemic transplantation of genetically engineered bone marrow …