Objective: To evaluate the safety and efficacy of abatacept during 2 years of the ATTAIN (A
batacept T rial in T reatment of A nti-TNF IN adequate responders) trial in patients with …

Targeted delivery of therapeutics possesses the potential to localize therapeutic agents to a
specific tissue as a mechanism to enhance treatment efficacy and abrogate side effects …

The systemic vasculitides are multisystem disorders with considerable mortality and
morbidity and frequent relapses. In the absence of reliable serological markers, accurate …

Background: Because periodontitis presents many similarities with rheumatoid arthritis (RA)
with regard to tumor necrosis factor‐alpha (TNF‐α)‐induced bone resorption, the benefits of …

Objective. To identify factors predicting response to first TNF blocking treatment course in
patients with established RA with a special focus on gender differences. Methods. Patients …

Inflammatory arthritis and especially rheumatoid arthritis (RA) is common and affects 1% of
the population. The prognosis of RA remains uncertain as it runs a variable and …

Objectives. To study treatment response rates of RA patients undergoing second-and third-
line anti-TNF therapy and to identify baseline predictors of response to second-line …

OBJECTIVE: To investigate longterm efficacy/safety of infliximab over 2 years in patients with
active psoriatic arthritis (PsA). METHODS: Initially, 104 patients were randomized to receive …

As in previous years, the consensus group to consider the use of biological agents in the
treatment of rheumatic diseases met during the 10th Annual Workshop on Advances in …

Objective To clarify the glucose‐6‐phosphate isomerase (GPI)–specific CD4+ T cell lineage
involved in GPI‐induced arthritis and to investigate their pathologic and regulatory roles in …