Rheumatoid arthritis (RA) is a chronic disease that affects and potentially destroys the joints
of the appendicular skeleton. The precise and reproducible quantification of the progression …

Background Tumour necrosis factor (TNF)‐alpha inhibitors are a major advance in the
management of inflammatory bowel disease but increase the risk for tuberculosis (TB). Aim …

Tumor necrosis factor α (TNFα), a pro-inflammatory cytokine, enhances the development of
pain and hyperalgesia, although the molecular mechanisms are not well understood. This …

OBJECTIVE: To evaluate the effect of rituximab treatment on health-related quality of life
(HRQOL) in patients with active rheumatoid arthritis (RA), who have had an inadequate …

Background: Anti-tumor necrosis factor (TNF) biologic agents are effective in treating
rheumatoid arthritis (RA). Information on patient persistence with biologic anti-TNF therapies …

Infiltration by inflammatory cells, thickening of the lining layer, and destructive invasion into
cartilage and bone are pathognomic features of the synovium in rheumatoid arthritis (RA) …

Objectives. We monitored the mRNA expression profiles of peripheral blood cells during
treatment with a TNF-α inhibitor, infliximab, in patients with RA. Using a DNA microarray …

Background Evaluate the potential role of p38 inhibitors for the treatment of osteoarthritis
using an animal model of joint degeneration (iodoacetate-induced arthritis) and a pain …

Objective. To investigate the long-term response to biological therapies in AS in a real life
clinical setting and to quantify non-response and response to 'switching'therapies in these …

Abstract Objective Spondylarthritis (SpA) and rheumatoid arthritis (RA) have different
patterns of bone damage, with more pronounced bone erosions in RA. The RANK/RANKL …