Objective Infliximab treatment results in a decrease in synovial cellularity as early as 48
hours after initiation of therapy in patients with rheumatoid arthritis (RA). This study was …

Objective Human neutrophils express both activating and inhibitory Fcγ receptors (FcγR),
and their relative expression determines the inflammatory response to immune complexes …

Objective To compare the value of reporting treatment effects in rheumatoid arthritis (RA) as
relative change from baseline (eg, American College of Rheumatology [ACR] responder …

Background: In some patients with psoriasis the inflammatory process fueling skin lesions
also afflicts their joints in a condition called psoriatic arthritis. TNF-α has been shown to play …

Tumor necrosis factor alpha (TNF) is an important cell-signaling component of the immune
system. Since its discovery over 20 years ago, much has been learned about its functions …

Objective To assess cost-effectiveness of abatacept in patients with rheumatoid arthritis (RA)
with inadequate response to tumor necrosis factor-α antagonists (anti-TNF). Methods We …

Rheumatoid arthritis (RA) is a heterogeneous disease with unknown etiology. Here we
aimed to distinguish RA subtypes based on peripheral blood (PB) gene expression profiles …

Rheumatoid arthritis (RA) is a systemic autoimmune disorder characterized by inflammation
involving large and small joints. Systemic manifestations as well as involvement of paraoral …

A series of coumarin types MMP inhibitors were designed based on gelastatin
hydroxamates (1) and evaluated for TACE, cellular TNF-α, and NO inhibitory activities …

Significant advances in the diagnosis and therapy for uveitis have been made to improve the
quality of care for patients with ocular inflammatory diseases. While traditional ophthalmic …