Relation between menin expression and NF-κB activity in an intestinal cell line

A Theillaumas, M Blanc, C Couderc, G Poncet… - Molecular and cellular …, 2008 - Elsevier
In a previous study, we demonstrated that the Men1 gene is mainly expressed in the
proliferative crypt compartment of the small intestine and that a reduction of menin …

Menin regulates endocrine diseases by controlling histone modification and gene transcription

SB Gao, X Hua, GH Jin - Annales d'endocrinologie, 2008 - Elsevier
Multiple endocrine neoplasia type 1 (MEN1), a human familial tumor syndrome, results from
mutations in the Men1 gene. Although much progress has been made in demonstrating the …

Genetic disorders of calcium and phosphate homeostasis

HW Jüppner, RV Thakker - Saunders Elsevier Company …, 2008 - books.google.com
Calcium and phosphate homeostasis is essential for bone integrity and involves several
different hormonal regulators that act on kidney, intestine, and bone. For example …

Multiple endocrine neoplasia

TC Lairmore - Surgery: Basic Science and Clinical Evidence, 2008 - Springer
Cancer is a genetic disease. Neoplastic transformation is characterized by a stepwise
accumulation of genetic damage within a cell that results in the acquisition of increasingly …

[PDF][PDF] ALTERED EXPRESSION AND PROMOTER METHYLATION OF THE MEN1 TUMOR SUPPRESSOR IN PANCREATIC DUCTAL ADENOCARCINOMA

I Cavallari, F Rende, M Silic-Benussi, A Martines… - academia.edu
Loss of Menin, a tumor suppressor coded by the MEN1 gene, is a key factor in the
pathogenesis of multiple endocrine neoplasia type 1 (MEN1) and in a percentage of …

Pancreatic Endocrine Tumourigenesis: Genes of potential importance

TA Johansson - 2008 - diva-portal.org
In addition, combined RNA interference and microarray expression analysis in the
pancreatic endocrine cell line BON1 identified 158 target genes of ASCL1. For two of these …