Caveolae are flask-shaped invaginations of the plasma membrane that are present in most
structural cells. They owe their characteristic Ω-shape to complexes of unique proteins, the …

Although several mechanisms have been proposed to explain the putative role of β-
carotene in cancer, no studies have investigated a possible influence of β-carotene on …

Pancreatic ductal adenocarcinoma is the fourth most common cause of cancer death, but the
prognosis and management of patients have remained unchanged despite the progress in …

Motivation: Genomic instability is one of the fundamental factors in tumorigenesis and tumor
progression. Many studies have shown that copy-number abnormalities at the DNA level are …

Caveolin-1 (cav-1) is a major structural protein of caveolae, small invaginations of the
plasma membrane that integrate and regulate signaling pathways involved in cell growth …

Interest in investigating cytotoxic therapy has increased dramatically since a survival
advantage was demonstrated in 2 phase III trials investigating docetaxel-based therapy in …

Aberrant (glyco) sphingolipid expression deeply affects several properties of tumor cells that
are involved in tumor progression and metastasis formation: cell adhesion (to the …

Peroxisome proliferator‐activated receptor‐gamma (PPARγ), one of three ligand‐activated
transcription factors named PPAR, has been identified as a molecular target for cancer …

目的检测窖蛋白1 (Cav-1) 在非小细胞肺癌(NSCLC) 中的蛋白表达以及启动子的甲基化状况,
探讨Cav-1 基因在NSCLC 中的作用及其临床意义. 方法应用免疫组织化学(SP 法) …

Caveolin-1 and flotillin-1 belong to plasma membrane microdomains. They are
characterized by peculiar lipid and protein composition and are involved in fundamental …