Direct interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II

K Nordick, MG Hoffman, JL Betz, JA Jaehning - Eukaryotic cell, 2008 - Am Soc Microbiol
ABSTRACT The Paf1 complex (Paf1, Ctr9, Cdc73, Rtf1, and Leo1) is normally associated
with RNA polymerase II (Pol II) throughout the transcription cycle. However, the loss of either …

[HTML][HTML] The Paf1 complex has functions independent of actively transcribing RNA polymerase II

CL Mueller, SE Porter, MG Hoffman, JA Jaehning - Molecular cell, 2004 - cell.com
The yeast Paf1 complex, minimally composed of Paf1, Ctr9, Cdc73, Rtf1, and Leo1, was
originally isolated in association with RNA polymerase II (Pol II). Paf1 complex components …

Separation of the Saccharomyces cerevisiae Paf1 Complex from RNA Polymerase II Results in Changes in Its Subnuclear Localization

SE Porter, KL Penheiter, JA Jaehning - Eukaryotic Cell, 2005 - Am Soc Microbiol
ABSTRACT The yeast Paf1 complex (Paf1C), composed of Paf1, Ctr9, Cdc73, Rtf1, and
Leo1, associates with RNA polymerase II (Pol II) at promoters and in the actively transcribed …

[HTML][HTML] From transcription to mRNA: PAF provides a new path

E Rosonina, JL Manley - Molecular cell, 2005 - cell.com
Two new studies (Penheiter et al.[2005] and Sheldon et al.[2005], this issue of Molecular
Cell) reveal a novel connection between transcription and pre-mRNA processing: the Paf1 …

Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex

CL Mueller, JA Jaehning - Molecular and cellular biology, 2002 - Am Soc Microbiol
Abstract The Saccharomyces cerevisiae Paf1-RNA polymerase II (Pol II) complex is
biochemically and functionally distinct from the Srb-mediator form of Pol II holoenzyme and …

The Paf1 complex: platform or player in RNA polymerase II transcription?

JA Jaehning - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2010 - Elsevier
The Paf1 complex (Paf1C), composed of the proteins Paf1, Ctr9, Cdc73, Rtf1, and Leo1,
accompanies RNA polymerase II (pol II) from the promoter to the 3′ end formation site of …

[HTML][HTML] Leo1 subunit of the yeast paf1 complex binds RNA and contributes to complex recruitment

JL Dermody, S Buratowski - Journal of Biological Chemistry, 2010 - ASBMB
The Paf1 complex (Paf1C) affects RNA polymerase II transcription by coordinating co-
transcriptional chromatin modifications and helping recruit mRNA 3′ end processing …

[HTML][HTML] A posttranscriptional role for the yeast Paf1-RNA polymerase II complex is revealed by identification of primary targets

KL Penheiter, TM Washburn, SE Porter, MG Hoffman… - Molecular cell, 2005 - cell.com
Summary The yeast Paf1 complex (Paf1C: Paf1, Cdc73, Ctr9, Rtf1, and Leo1) is associated
with RNA Polymerase II (Pol II) at promoters and coding regions of transcriptionally active …

Drosophila Paf1 modulates chromatin structure at actively transcribed genes

K Adelman, W Wei, MB Ardehali, J Werner… - … and cellular biology, 2006 - Am Soc Microbiol
The Paf1 complex in yeast has been reported to influence a multitude of steps in gene
expression through interactions with RNA polymerase II (Pol II) and chromatin-modifying …

The roles of the Paf1 complex and associated histone modifications in regulating gene expression

EM Crisucci, KM Arndt - Genetics research international, 2011 - Wiley Online Library
The conserved Paf1 complex (Paf1C) carries out multiple functions during transcription by
RNA polymerase (pol) II, and these functions are required for the proper expression of …