Transforming growth factor β (TGF-β) signaling facilitates metastasis in advanced
malignancy. While a number of protein-encoding genes are known to be involved in this …

Breast cancer is the most common type of cancer among women worldwide, and metastasis
represents the most devastating stage of the disease. Recent studies have revealed that …

Objectives MicroRNAs (miRNAs) have been proved to play important role in development of
various cancers, including non-small cell lung cancer (NSCLC). Our previous studies have …

Background: Previous reports have shown a mutual negative feedback loop between
microRNA (miR)-206 and estrogen receptor (ER) expression. Furthermore, decreased miR …

The transforming growth factor β (TGFβ) pathway plays critical roles during cancer cell
epithelial-mesenchymal transition (EMT) and metastasis. SMAD7 is both a transcriptional …

Down-regulation of miR-138 (microRNA-138) has been frequently observed in various
cancers, including HNSCC (head and neck squamous cell carcinoma). Our previous studies …

The transforming growth factor-β (TGF-β) signalling pathway participates in various
biological processes. Dysregulation of Smad4, a central cellular transducer of TGF-β …

Abstract TGF-β1-induced epithelial-mesenchymal transition (EMT) has been proved to be
associated with metastasis of breast cancer cells. We attempted to detect a novel …

Transforming growth factor-β (TGF-β)-induced epithelial-mesenchymal transition (EMT) has
been shown to be related to the pathogenesis of various diseases including lung cancer …

MicroRNA-181 (miR-181) is a multifaceted miRNA that has been implicated in many cellular
processes such as cell fate determination and cellular invasion. While miR-181 is often …