Dietary restriction is known to promote longevity in a variety of eukaryotic organisms. Most
studies of dietary restriction have been performed on animals bred for many generations …

In Caenorhabditis elegans, several manipulations that affect nutrition slow development,
reduce fecundity, and increase life span. These are viewed as dietary restriction (DR) and …

The nematode Caenorhabditis elegans has proved to be an excellent model organism for
the study of development and aging. Many aging mutants have been discovered in the past …

Mutations that increase the longevity of the soil nematode Caenorhabditis elegans could
define genes involved in a process specific for aging. Alternatively, these mutations could …

Dietary restriction (DR) is the most consistent means of extending life span throughout the
animal kingdom. Multiple mechanisms by which DR may act have been proposed but none …

Background Dietary restriction (DR) increases life span and delays age-associated disease
in many organisms. The mechanism by which DR enhances longevity is not well …

Reduction of food intake without malnutrition or starvation is known to increase lifespan and
delay the onset of various age-related diseases in a wide range of species, including …

Aging is a degenerative process characterized by a progressive deterioration of cellular
components and organelles resulting in mortality. The nematode Caenorhabditis elegans …

Dietary restriction (DR) is a well-established intervention to extend lifespan across taxa.
Recent studies suggest that DR-driven lifespan extension can be cost-free, calling into …

The nematode Caenorhabditis elegans is a well-known model organism for research on
aging and life span, but very little is known about its ecology and natural history. The strain …