Excess body weight (overweight and obesity) is characterized by chronic hyperinsulinaemia
and insulin resistance, and is implicated both in cancer risk and cancer mortality. The list of …

The prevalence of obesity is rapidly increasing globally. Epidemiological studies have
associated obesity with a range of cancer types, although the mechanisms by which obesity …

Obesity is associated with a range of health outcomes that are of clinical and public health
significance, including cancer. Herein, we summarize epidemiologic and preclinical …

Obesity is a leading modifiable risk factor for the development of several epithelial
malignancies. In addition to increasing risk, obesity also confers worse prognosis for many …

Continuously rising trends in obesity-related malignancies render this disease spectrum a
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …

Obesity results from a chronic excessive accumulation of adipose tissue due to a long-term
imbalance between energy intake and expenditure. Available epidemiological and clinical …

The incidence of obesity in US adults has been steadily increasing over the past few
decades. Many comorbidities associated with obesity have been well-established such as …

Historically, cancer research has focused on identifying mutations or amplification of genes
within the tumor, which informed the development of targeted therapies against affected …

Obesity and components of energy imbalance, that is, excessive energy intake and
suboptimal levels of physical activity, are established risk factors for cancer incidence …

Obesity is a risk factor for cancer development and is associated with poor prognosis in
multiple tumor types. The positive energy balance linked with obesity induces a variety of …