Endothelial cells play essential roles in maintenance of vascular integrity, angiogenesis, and
wound repair. We show that an endothelial cell-restricted microRNA (miR-126) mediates …

Activation of the angiogenic program in endothelial cells is vital for normal embryonic
development and for physiological angiogenesis in the adult. In addition, angiogenesis is an …

Precise regulation of the formation, maintenance, and remodeling of the vasculature is
required for normal development, tissue response to injury, and tumor progression. How …

The effects and potential mechanisms of the vascular endothelial cell (EC)-enriched
microRNA-15a (miR-15a) on angiogenesis remain unclear. Here, we show a novel finding …

Rationale: Endothelial cells in situ are largely quiescent, and their isolation and culture are
associated with the switch to a proliferative phenotype. Objective: To identify antiangiogenic …

Aims Angiogenesis is a critical component of many pathological conditions in adult tissues
and is essential for embryonic development. MicroRNAs are indispensable for normal …

Objective—MicroRNA plays important roles in vascular biology, but the regulation of
endothelial-specific microRNA is not well characterized. MicroRNA-126 (miR-126) is highly …

Abstract Expression of microRNA (miR)-126 is enriched in endothelial cells (ECs) and
endothelial progenitor cells (EPCs). MiR-126 is considered a master regulator of …

Rationale: Formation and remodeling of the vasculature during development and disease
involve a highly conserved and precisely regulated network of attractants and repellants …

Rationale: MicroRNAs (miRNAs) are key regulators of vascular development and diseases.
The function and underlying mechanism of endothelial miRNAs have not been fully defined …