A simple, accurate and rapid method for simultaneous analysis of vancomycin and
ceftazidime in cerebrospinal fluid (CSF), utilizing high-performance liquid chromatography …

Vancomycin (VCM) is clinically used in treating patients with postoperative intracranial
infections. The cerebrospinal fluid (CSF) concentration of VCM varies greatly among …

Vancomycin (VAN), meropenem (MER), and valproate (VPA) are commonly used to treat
intracranial infection post-craniotomy and prevent associated epilepsy. To monitor their …

A reverse phase-liquid chromatographic method with UV detection at 280 nm is described
for simultaneous determination of ceftriaxone sodium and vancomycin hydrochloride …

What is known and objective To compare the penetration of vancomycin into cerebrospinal
fluid (CSF) in patients with postoperative intracranial infection and community‐acquired …

Background Penetration and concentration of vancomycin is still an elusive and complex
issue particularly in Cerebrospinal Fluid (CSF). The aim of this study was to clarify the …

Objective The purpose of the study was to investigate the pharmacokinetics of combined
intravenous (IV) and intracerebroventricular (ICV) vancomycin for patients with intracranial …

The objective of this study was to retrospectively investigate the influence of cerebral fluid
drainage on the serum concentrations and pharmacokinetic parameters of vancomycin …

Introduction Infectious disease and pharmacokinetic textbooks indicate that vancomycin has
poor penetration into the central nervous system due to its hydrophilic nature and high …

Our previous study indicates that cerebrospinal fluid (CSF) albumin level is a determinant of
CSF vancomycin concentration for postoperative neurosurgical patients. We aimed to …