The transcription factor NF-κB has served as a standard for inducible transcription factors for
more than 20 years. The numerous stimuli that activate NF-κB, and the large number of …

Nuclear factor-κB (NF-κB) consists of a family of transcription factors that play critical roles in
inflammation, immunity, cell proliferation, differentiation, and survival. Inducible NF-κB …

In the 20 years since its discovery, research into the NF-κB (nuclear factor-κB) family of
transcription factors has revealed an amazing diversity of functions. NF-κB proteins are …

The mammalian Rel/NF-κB family of transcription factors, including RelA, c-Rel, RelB, NF-
κB1 (p50 and its precursor p105), and NF-κB2 (p52 and its precursor p100), plays a central …

NF-κB is activated by many stimuli and NF-κB binding sites have been identified in a wide
variety of genes. Yet, NF-κB-dependent gene expression must be stimulus-and cell-type …

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Research on the biological function of nuclear factor-κB (NF-κB), a key mediator of inducible
transcription in the immune system, has traditionally focused on its role in the initiation of …

The transcription factor NF-κB has been the focus of intense investigation for nearly two
decades. Over this period, considerable progress has been made in determining the …

The involvement of the transcription factor NF-κB in a plethora of cellular activities has made
it one of the most studied proteins. The emerging understanding of new roles for NF-κB and …

NF-κB was first discovered and characterized 25 years ago as a key regulator of inducible
gene expression in the immune system. Thus, it is not surprising that the clearest biological …