Failure of two commercial indexes and spectral parameters to reflect the pharmacodynamic effect of desflurane on EEG
S Kreuer, J Bruhn, R Ellerkmann, S Ziegeler… - Journal of clinical …, 2008 - Springer
Objective We compared two PK/PD models, one with and one without a plateau effect.
Bispectral (BIS, Aspect Medical Systems, Natick, MA, version XP) and Narcotrend™(NCT …
Bispectral (BIS, Aspect Medical Systems, Natick, MA, version XP) and Narcotrend™(NCT …
Comparative pharmacodynamic modeling of desflurane, sevoflurane and isoflurane
S Kreuer, J Bruhn, W Wilhelm, U Grundmann… - Journal of clinical …, 2009 - Springer
Background We compared dose–response curves of the hypnotic effects of desflurane,
sevoflurane and isoflurane. In addition, we analyzed the k e0 values of the different …
sevoflurane and isoflurane. In addition, we analyzed the k e0 values of the different …
Narcotrend or bispectral index monitoring during desflurane-remifentanil anesthesia: a comparison with a standard practice protocol
S Kreuer, J Bruhn, C Stracke, L Aniset… - Anesthesia & …, 2005 - journals.lww.com
IMPLICATIONS: Monitoring the electroencephalogram with Narcotrend or Bispectral Index
during desflurane-remifentanil anesthesia only slightly reduces recovery times when …
during desflurane-remifentanil anesthesia only slightly reduces recovery times when …
Comparative pharmacodynamic modeling using bispectral and narcotrend-index with and without a pharmacodynamic plateau during sevoflurane anesthesia
S Kreuer, J Bruhn, E Walter, R Larsen… - Anesthesia & …, 2008 - journals.lww.com
BACKGROUND: We compared two pharmacodynamic models, one with and one without a
plateau effect. Bispectral indices (BIS, Aspect Medical Systems, Natick, MA, version XP) and …
plateau effect. Bispectral indices (BIS, Aspect Medical Systems, Natick, MA, version XP) and …
Approximate entropy as an electroencephalographic measure of anesthetic drug effect during desflurane anesthesia
J Bruhn, H Röpcke, A Hoeft - The Journal of the American Society of …, 2000 - pubs.asahq.org
Background The authors hypothesized that the electroencephalogram (EEG) during higher
anesthetic concentrations would show more" order" and less" randomness" than at lower …
anesthetic concentrations would show more" order" and less" randomness" than at lower …
The correlation of the Narcotrend® Index and classical electroencephalographic parameters with endtidal desflurane concentrations and hemodynamic parameters …
F Weber, M Gruber, K Taeger - Pediatric Anesthesia, 2005 - Wiley Online Library
Summary Background: The Narcotrend® Index (NI) for assessment of depth of anesthesia
by analysis of the electroencephalogram (EEG), is potentially a pharmacodynamic measure …
by analysis of the electroencephalogram (EEG), is potentially a pharmacodynamic measure …
Application of Bispectral index® and Narcotrend® index to the measurement of the electroencephalographic effects of Isoflurane with and without burst suppression
S Kreuer, J Bruhn, R Larsen, U Grundmann… - The Journal of the …, 2004 - pubs.asahq.org
Background The Narcotrend monitor (MonitorTechnik, Bad Bramstedt, Germany) has
recently been introduced as an intraoperative monitor of anesthetic state, based on a …
recently been introduced as an intraoperative monitor of anesthetic state, based on a …
Surgical stimulation shifts EEG concentration–response relationship of desflurane
H Röpcke, B Rehberg… - The Journal of the …, 2001 - pubs.asahq.org
Background Anesthesiologists routinely increase the delivered anesthetic concentration
before surgical stimulation in anticipation of increased anesthetic requirement to achieve …
before surgical stimulation in anticipation of increased anesthetic requirement to achieve …
Comparison of BIS and AAI as measures of anaesthetic drug effect during desflurane–remifentanil anaesthesia
S Kreuer, J Bruhn, R Larsen, C Bauer… - Acta …, 2004 - Wiley Online Library
Background: Autoregressive modelling with exogenous input of the middle‐latency auditory
evoked potential has been developed for monitoring of anaesthetic depth. This study was …
evoked potential has been developed for monitoring of anaesthetic depth. This study was …
A comparison of spectral edge, delta power, and bispectral index as EEG measures of alfentanil, propofol, and midazolam drug effect
V Billard, PL Gambus, N Chamoun… - Clinical …, 1997 - Wiley Online Library
Background The effects of anesthetic drugs on electroencephalograms (EEG) have been
studied to develop the EEG as a measure of anesthetic depth. Bispectral analysis is a new …
studied to develop the EEG as a measure of anesthetic depth. Bispectral analysis is a new …
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