Epoxyeicosatrienoic acids (EETs) are cytochrome P450 metabolites of arachidonic acid,
which function in the brain to regulate cerebral blood flow and protect against ischemic brain …

Epoxide hydrolases comprise a family of enzymes important in detoxification and conversion
of lipid signaling molecules, namely epoxyeicosatrienoic acids (EETs), to their supposedly …

The P450 eicosanoids epoxyeicosatrienoic acids (EETs) are produced in brain and perform
important biological functions, including protection from ischemic injury. The beneficial effect …

Background and Purpose—Cytochrome P450 epoxygenase metabolizes arachidonic acid
to epoxyeicosatrienoic acids (EETs). EETs are produced in the brain and perform important …

Soluble Epoxide Hydrolase (sEH) is a key enzyme in the metabolism and termination of
action of epoxyeicosatrienoic acids, derivatives of arachidonic acid, which are protective …

Soluble epoxide hydrolase (sEH) metabolizes epoxyeicosatrienoic acids and represents a
novel therapeutic target in cardiovascular disease treatment. We investigated the …

Soluble epoxide hydrolase (sEH) is a phase-I xenobiotic metabolizing enzyme having both
an N-terminal phosphatase activity and a C-terminal epoxide hydrolase activity …

Soluble epoxide hydrolase (sEH) is a key enzyme in the metabolic conversion and
degradation of P450 eicosanoids termed epoxyeicosatrienoic acids (EETs). Genetic …

Epoxyeicosatrienoic acids (EETs) are fatty acid signaling molecules synthesized by
cytochrome P450 epoxygenases from arachidonic acid. The biological activity of EETs is …

The P450 eicosanoids epoxyeicosatrienoic acids (EETs) are endogenous lipid mediators
produced in the brain by P450 epoxygenases and metabolized through multiple pathways …