Small non-coding RNAs in animal development
The modulation of gene expression by small non-coding RNAs is a recently discovered level
of gene regulation in animals and plants. In particular, microRNAs (miRNAs) and Piwi …
of gene regulation in animals and plants. In particular, microRNAs (miRNAs) and Piwi …
[HTML][HTML] MicroRNA function in animal development
E Wienholds, RHA Plasterk - FEBS letters, 2005 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNA molecules that post-transcriptionally
regulate gene expression by base-pairing to mRNAs. Hundreds of miRNAs have been …
regulate gene expression by base-pairing to mRNAs. Hundreds of miRNAs have been …
[HTML][HTML] Micro RNAs in animal development
RHA Plasterk - Cell, 2006 - cell.com
Micro RNAs (miRNAs) are∼ 22 nucleotide single-stranded noncoding RNA molecules that
bind to target messenger RNAs (mRNAs) and silence their expression. This Essay explores …
bind to target messenger RNAs (mRNAs) and silence their expression. This Essay explores …
Small RNAs: regulators and guardians of the genome
CY Chu, TM Rana - Journal of cellular physiology, 2007 - Wiley Online Library
Small non‐coding RNAs comprise several classes and sizes, but all share a unifying
function in cellular physiology: epigenetic regulation of gene expression. Here, we review …
function in cellular physiology: epigenetic regulation of gene expression. Here, we review …
A PCR-based method for detection and quantification of small RNAs
Recent cloning efforts have identified hundreds of thousands of small RNAs including micro
RNAs (miRNAs), Piwi-interacting RNAs (piRNAs), and small nucleolar RNAs (snoRNAs) …
RNAs (miRNAs), Piwi-interacting RNAs (piRNAs), and small nucleolar RNAs (snoRNAs) …
Biogenesis of small RNAs in animals
VN Kim, J Han, MC Siomi - Nature reviews Molecular cell biology, 2009 - nature.com
Small RNAs of 20–30 nucleotides can target both chromatin and transcripts, and thereby
keep both the genome and the transcriptome under extensive surveillance. Recent progress …
keep both the genome and the transcriptome under extensive surveillance. Recent progress …
[HTML][HTML] The evolution and functional diversification of animal microRNA genes
N Liu, K Okamura, DM Tyler, MD Phillips, WJ Chung… - Cell research, 2008 - nature.com
Abstract microRNAs (miRNAs) are an abundant class of∼ 22 nucleotide (nt) regulatory
RNAs that are pervasive in higher eukaryotic genomes. In order to fully understand their …
RNAs that are pervasive in higher eukaryotic genomes. In order to fully understand their …
[HTML][HTML] MicroRNAs: genomics, biogenesis, mechanism, and function
DP Bartel - cell, 2004 - cell.com
MicroRNAs (miRNAs) are endogenous∼ 22 nt RNAs that can play important regulatory
roles in animals and plants by targeting mRNAs for cleavage or translational repression …
roles in animals and plants by targeting mRNAs for cleavage or translational repression …
[HTML][HTML] Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegansdevelopment
Abstract Background Small non-coding RNAs, including microRNAs (miRNAs), serve an
important role in controlling gene expression during development and disease. However …
important role in controlling gene expression during development and disease. However …
Small RNAs in early mammalian development: from gametes to gastrulation
N Suh, R Blelloch - Development, 2011 - journals.biologists.com
Small non-coding RNAs, including microRNAs (miRNAs), endogenous small interfering
RNAs (endo-siRNAs) and Piwi-interacting RNAs (piRNAs), play essential roles in …
RNAs (endo-siRNAs) and Piwi-interacting RNAs (piRNAs), play essential roles in …