Abstract The RelA (p65) NF-κB (nuclear factor κB) subunit contains an extremely active C-
terminal transcriptional activation domain, required for its cellular function. In the present …

Phosphorylation of the RelA (p65) NF-κB (nuclear factor κB) subunit has been previously
shown to modulate its ability to induce or repress transcription. In the present study we have …

The NF-κB transcription factor complex is composed of two proteins, designated p50 and
p65, both having considerable homology to the product of the rel oncogene. We present …

Binding sites for the nuclear factor (NF)-κB transcription factor have been identified within
control regions of many genes involved in inflammatory and immune responses. Such κB …

The NF-κB family member RelB has many properties not shared by other family members
such as restricted subunit association and lack of regulation by the classical IκB proteins. We …

Nuclear factor κB (NF-κB)/Rel transcription factors are key regulators of a variety of genes
involved in immune and inflammatory responses, growth, differentiation, apoptosis, and …

Nuclear factor kappa B (NFκB) is a dimeric transcription factor comprised of five family
members RelA (p65), RelB, c-Rel, p50 and p52. NFκB signalling is complex and controls a …

The association of the NF-κB p65/p50 dimer with IκBα plays a pivotal role in regulating its
nuclear translocation and gene transcription. In addition, serine phosphorylation at various …

Alterations of NF-κB family members have been found to be associated with various forms of
lymphoid malignancies. In order to determine whether alterations of the RelA gene are …

RelB is an unusual member of the NF-κB transcription factor family that acts as both a
transcriptional activator as well as a repressor of NF-κB-dependent gene expression …