MicroRNAs (miRNAs or miRs) regulate diverse normal and abnormal cell functions. We
have identified a regulatory pathway in normal megakaryopoiesis, involving the PLZF …

MicroRNAs are small noncoding RNAs that regulate cellular development by interfering with
mRNA stability and translation. We examined global microRNA expression during the …

OBJECTIVE: MicroRNAs (miRNAs) are short noncoding RNAs capable of exerting dramatic
effects by postranscriptionally regulating numerous messenger RNA targets. Toll-like …

MicroRNAs play important roles in cell differentiation by acting as translational inhibitors of
specific target genes. Here we show that human granulocytic differentiation is controlled by …

Emerging evidence has shown that microRNAs have key roles in regulating various normal
physiological processes, whereas their deregulated expression is correlated with various …

Although microRNAs (miRNAs) are increasingly linked to various physiologic processes,
including hematopoiesis, their function in the myeloid development is poorly understood. We …

Epigenetic modifications regulate developmental genes involved in stem cell identity and
lineage choice. NFI-A is a posttranscriptional microRNA-223 (miR-223) target directing …

microRNAs are a highly conserved class of noncoding RNAs with important regulatory
functions in proliferation, apoptosis, development, and differentiation. To discover novel …

MicroRNAs (miRNAs) are key regulators of gene expression that help direct normal
differentiation and malignant transformation of hematopoietic cells. This review summarizes …

Despite advances in defining the critical molecular determinants for leukemia stem cell
(LSC) generation and maintenance, little is known about the roles of microRNAs in LSC …