Dysfunction in the hypothalamic GABAergic system has been implicated in panic syndrome
in humans. Furthermore, several studies have implicated the hypothalamus in the …

Objective. To evaluate the effectiveness of amitriptyline 2%/baclofen 2% cream (ABC) in
treating provoked vestibulodynia (PV). Materials and Methods. In this retrospective …

“Dor” é experiência vivenciada por quase todos os seres humanos. É conceituada como
“experiência sensitiva e emocional desagradável decorrente ou descrita em termos de …

The objective of the present study was to examine whether milnacipran, a serotonin–
noradrenaline reuptake inhibitor, has an analgesic effect in rats with neuropathic pain. In …

The use of opioids for the treatment of chronic non-cancer pain has become more
widespread recently. Available data support the short-term use of opioids in clearly defined …

The ascending nociceptive control (ANC), a novel spinostriatal pain modulation pathway,
mediates a form of pain-induced analgesia referred to as noxious stimulus-induced …

The aim of this study was to investigate the effect of unilateral limb pain on sensitivity to pain
on each side of the forehead. In the first experiment, pressure-pain thresholds and …

Brainstem structures engage descending facilitatory and inhibitory neurones to potentiate or
suppress the passage of sensory inputs from spinal loci to the brain. The final output for this …

Background Peripheral neuropathy is a common complication of diabetes, whereby pain
control is the most difficult issue. The outcomes of existing treatment options are far from …

In the hamster brainstem estrogen receptor-α-immunoreactive neurons (ER-α-IR) are
present in the nucleus para-retroambiguus (NPRA), located in the caudal ventrolateral …