Early phase pharmacokinetics but not pharmacodynamics are influenced by propofol infusion rate

K Masui, M Kira, T Kazama, S Hagihira… - The Journal of the …, 2009 - pubs.asahq.org
Background Conventional compartmental pharmacokinetic models wrongly assume
instantaneous drug mixing in the central compartment, resulting in a flawed prediction of …

Early phase pharmacokinetics but not pharmacodynamics are influenced by propofol infusion rate

K Masui, M Kira, T Kazama, S Hagihira, E Mortier… - …, 2009 - biblio.ugent.be
Background: Conventional compartmental pharmacokinetic models wrongly assume
instantaneous drug mixing in the central compartment, resulting in a flawed prediction of …

Early Phase Pharmacokinetics but Not Pharmacodynamics Are Influenced by Propofol Infusion Rate

K Masui, M Kira, T Kazama, S Hagihira, EP Mortier… - …, 2009 - research.rug.nl
Background: Conventional compartmental pharmacokinetic models wrongly assume
instantaneous drug mixing in the central compartment, resulting in a flawed prediction of …

Early phase pharmacokinetics but not pharmacodynamics are influenced by propofol infusion rate

K Masui, M Kira, T Kazama, S Hagihira, EP Mortier… - 2009 - pubmed.ncbi.nlm.nih.gov
Background Conventional compartmental pharmacokinetic models wrongly assume
instantaneous drug mixing in the central compartment, resulting in a flawed prediction of …

[PDF][PDF] Early Phase Pharmacokinetics but Not Pharmacodynamics Are Influenced by Propofol Infusion Rate

K Masui, M Kira, T Kazama, S Hagihira, EP Mortier… - Anesthesiology, 2009 - core.ac.uk
Methods: Fifty patients were randomly assigned to one of five groups to receive 1.2 mg/kg
propofol given with the rate of 10 to 160 mg· kg 1· h 1. Arterial blood samples were taken …

Early phase pharmacokinetics but not pharmacodynamics are influenced by propofol infusion rate.

K Masui, M Kira, T Kazama, S Hagihira, EP Mortier… - …, 2009 - europepmc.org
Background Conventional compartmental pharmacokinetic models wrongly assume
instantaneous drug mixing in the central compartment, resulting in a flawed prediction of …

[引用][C] Early Phase Pharmacokinetics but Not Pharmacodynamics Are Influenced by Propofol Infusion Rate

K MASUI, M KIRA, T KAZAMA… - Anesthesiology …, 2009 - pascal-francis.inist.fr
Early Phase Pharmacokinetics but Not Pharmacodynamics Are Influenced by Propofol
Infusion Rate CNRS Inist Pascal-Francis CNRS Pascal and Francis Bibliographic …

[PDF][PDF] Early Phase Pharmacokinetics but Not Pharmacodynamics Are Influenced by Propofol Infusion Rate

K Masui, M Kira, T Kazama, S Hagihira… - …, 2009 - backoffice.biblio.ugent.be
Methods: Fifty patients were randomly assigned to one of five groups to receive 1.2 mg/kg
propofol given with the rate of 10 to 160 mg· kg 1· h 1. Arterial blood samples were taken …

Early Phase Pharmacokinetics but Not Pharmacodynamics Are Influenced by Propofol Infusion Rate

K Masui, M Kira, T Kazama, S Hagihira, EP Mortier… - Anesthesiology, 2009 - cir.nii.ac.jp
抄録< jats: sec>< jats: title> Background</jats: title>< jats: p> Conventional compartmental
pharmacokinetic models wrongly assume instantaneous drug mixing in the central …