Integrative hierarchical models have sought to account for the extensive comorbidity
between various internalizing disorders in terms of broad individual difference factors these …

Although affective modification of the startle reflex is a robust phenomenon, it does not occur
universally. Research is reviewed suggesting that affective startle modification varies …

Current initiatives such as the National Institute of Mental Health's Research Domain Criteria
project aim to reorganize classification of mental disorders along neurobiological lines …

The purpose of this chapter is to examine contemporary psychophysiological accounts of
interactions between attention and affect as manifested by research on orienting and …

Startle reflex potentiation versus startle attenuation to unpleasant versus pleasant stimuli
likely reflect priming of the defensive versus appetitive motivational systems, respectively …

Objective: To provide an overview of startle reflex methodologies applied to the examination
of emotional and motivational states in humans and to review the findings in different forms …

Heightened reactivity to uncertain threat (U-threat) is an important individual difference factor
that may characterize fear-based internalizing psychopathologies (IPs) and distinguish them …

This chapter considers the concept of negative affect as it can be measured physiologically,
and can serve as a unifying dimension across the anxiety disorder spectrum. It begins with …

Abstract The National Institute of Mental Health's Research Domain Criteria initiative is a
research framework designed toward understanding psychopathology as abnormalities of …

The authors examined the time course of affective responding associated with different
affective dimensions--anxious apprehension, anxious arousal, and anhedonic depression …