Transforming growth factor‐beta (TGFβ) is a secreted cytokine, which intricately controls a
plethora of physiological and pathological processes during development and …

The transforming growth factor β (TGFβ) signaling pathway is a key player in metazoan
biology, and its misregulation can result in tumor development. The regulatory cytokine …

The transforming growth factor‐β (TGF‐β) signalling pathway plays a critical and dual role in
the progression of human cancer. During the early phase of tumour progression, TGF‐β acts …

A ubiquitously expressed cytokine, transforming growth factor-beta (TGF-β) plays a
significant role in various ongoing cellular mechanisms. The gain or loss-of-function of TGF …

TGFβ acts as a potent tumor suppressor and tumor promoter in a context dependent
manner. Tumor suppressive functions include inhibition of cell proliferation, induction of …

Transforming growth factor-β (TGFβ) family members are structurally and functionally related
cytokines that have diverse effects on the regulation of cell fate during embryonic …

Transforming growth factor-β (TGFβ) has a crucial role in tissue homeostasis and disruption
of the TGFβ pathway has been implicated in many human diseases including cancer. As a …

Transforming growth factor-β (TGF-β) induces a pleiotropic pathway that is modulated by the
cellular context and its integration with other signaling pathways. In cancer, the pleiotropic …

Transforming growth factor (TGF) β1 is a potent growth inhibitor, with tumor-suppressing
activity. Cancers are often refractile to this growth inhibition either because of genetic loss of …

The transforming growth factor‐beta (TGFβ) superfamily encompasses widespread and
evolutionarily conserved polypeptide growth factors that regulate and orchestrate growth …