Other than its well-recognized effects on reproductive physiology, estrogen has important
actions in a wide variety of other body systems with important examples including bone …

Background: Estrogen receptors (ER) belong to the super-family of the nuclear hormone
receptors which act as ligand-regulated transcription factor to control a diverse set of …

Estrogens are present in both men and women; they are usually present at significantly
higher levels in women of reproductive age. They promote the development of female …

Genetic variation in estrogen-metabolizing genes and estrogen receptors influences
estrogen metabolism and can potentially modify, at least in part, individual responses to …

Estrogen hormones play critical roles in the regulation of many tissue functions. The effects
of estrogens are primarily mediated by the estrogen receptors (ER) α and β. ERs are ligand …

The purpose of this paper is to review potential novel functional pathways by which estradiol
and estrogenic compounds elicit biological responses in mammals. We will limit our …

Abstract Objective Estrogen receptor 1 (ESR1) plays an important role in various estrogen-
related diseases, the incidences of which are significantly lower in the Japanese population …

One or more common variants in estrogen receptor-α are associated with a differential
response to hormone replacement therapy in several domains of estrogen action. However …

The estrogens are female sex hormones that are involved in a variety of physiological
processes, including reproductive development and function, wound healing, and bone …

The estrogen receptors (ERs), ERα and ERβ, play a central role in mediating the biological
effects of estrogen. The transcription rate of estrogen target genes is determined by several …