[HTML][HTML] Kekkon5 is an extracellular regulator of BMP signaling

TA Evans, H Haridas, JB Duffy - Developmental biology, 2009 - Elsevier
Precise spatial and temporal control of Drosophila Bone Morphogenetic Protein (BMP)
signaling is achieved by a host of extracellular factors that modulate ligand distribution and …

[HTML][HTML] The BMP-binding protein Crossveinless 2 is a short-range, concentration-dependent, biphasic modulator of BMP signaling in Drosophila

M Serpe, D Umulis, A Ralston, J Chen, DJ Olson… - Developmental cell, 2008 - cell.com
In Drosophila, the secreted BMP-binding protein Short gastrulation (Sog) inhibits signaling
by sequestering BMPs from receptors, but enhances signaling by transporting BMPs through …

Shaping BMP morphogen gradients in the Drosophila embryo and pupal wing

MB O'Connor, D Umulis, HG Othmer, SS Blair - 2006 - journals.biologists.com
In the early Drosophila embryo, BMP-type ligands act as morphogens to suppress neural
induction and to specify the formation of dorsal ectoderm and amnioserosa. Likewise, during …

Schnurri transcription factors from Drosophila and vertebrates can mediate Bmp signaling through a phylogenetically conserved mechanism

LC Yao, IL Blitz, DA Peiffer, S Phin, Y Wang, S Ogata… - 2006 - journals.biologists.com
Bone Morphogenetic Proteins (Bmps) are secreted growth factors that play crucial roles in
animal development across the phylogenetic spectrum. Bmp signaling results in the …

Regulation of BMP activity and range in Drosophila wing development

LA Raftery, DM Umulis - Current opinion in cell biology, 2012 - Elsevier
Bone morphogenetic protein (BMP) signaling controls development and maintenance of
many tissues. Genetic and quantitative approaches in Drosophila reveal that ligand isoforms …

[HTML][HTML] Mad linker phosphorylations control the intensity and range of the BMP-activity gradient in developing Drosophila tissues

A Aleman, M Rios, M Juarez, D Lee, A Chen… - Scientific reports, 2014 - nature.com
The BMP ligand Dpp, operates as a long range morphogen to control many important
functions during Drosophila development from tissue patterning to growth. The BMP signal …

[HTML][HTML] BMP-dependent gene repression cascade in Drosophila eggshell patterning

E Charbonnier, A Fuchs, LS Cheung, M Chayengia… - Developmental …, 2015 - Elsevier
Abstract Bone Morphogenetic Proteins (BMPs) signal by activating Smad transcription
factors to control a number of decisions during animal development. In Drosophila, signaling …

Phosphorylation of Mad controls competition between wingless and BMP signaling

E Eivers, H Demagny, RH Choi, EM De Robertis - Science signaling, 2011 - science.org
Bone morphogenetic proteins (BMPs) and Wnts are growth factors that provide essential
patterning signals for cell proliferation and differentiation. Here, we describe a molecular …

[HTML][HTML] Drosophila ML-DmD17-c3 cells respond robustly to Dpp and exhibit complex transcriptional feedback on BMP signaling components

SJ Neal, D Dolezal, N Jusić, F Pignoni - BMC developmental biology, 2019 - Springer
Background BMP signaling is involved in myriad metazoan developmental processes, and
study of this pathway in Drosophila has contributed greatly to our understanding of its …

[HTML][HTML] Heterodimerization-dependent secretion of bone morphogenetic proteins in Drosophila

M Bauer, G Aguilar, KA Wharton, S Matsuda… - Developmental cell, 2023 - cell.com
Combinatorial signaling is key to instruct context-dependent cell behaviors. During
embryonic development, adult homeostasis, and disease, bone morphogenetic proteins …