BACKGROUND: Inhaled hypertonic saline is used for bronchial challenge and sputum
induction in patients with chronic obstructive pulmonary disease (COPD). We studied the …

The present study aimed at delineating the mechanisms underlying the adverse response to
hypertonic saline inhalation in patients with chronic obstructive pulmonary disease (COPD) …

Background Oxygen desaturation during exercise is common in people with chronic
obstructive pulmonary disease (COPD). The aim of the study is to determine, in people with …

1444 AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE VOL 183
2011 cystic fibrosis (CF) to abnormal mucociliary clearance due to dysregulation of the …

Background: There is anecdotal evidence that nebulised saline relieves breathlessness at
rest in patients with severe chronic obstructive pulmonary disease (COPD). It is unclear …

Background Many trials of nebulized therapy have used nebulized saline as a" placebo".
However, nebulized isotonic saline is sometimes used to assist sputum expectoration and …

Background Physical exercise training is an evidence-based treatment in chronic obstructive
pulmonary disease, and patients' peak work rate is associated with reduced chronic …

Introduction Early pulmonary rehabilitation is recommended after a severe exacerbation of
chronic obstructive pulmonary disease (COPD). However, this is difficult to implement …

Background Inhaled hypertonic saline (HTS) improves quality of life and reduces pulmonary
exacerbations when given long term in patients with cystic fibrosis (CF). While increasingly …

Study objectives: Hypertonic saline solution inhalation is suspected to produce airway
inflammation. Design: The aim of this study was to verify this hypothesis by measuring …