The syncytiotrophoblast is a specialized epithelium derived from mononuclear
cytotrophoblasts that fuse to form this extensive syncytium. Dysferlin is expressed primarily …

Dysferlin (DYSF) and myoferlin (MYOF), members of the ferlin family of membrane proteins,
are co-expressed in human placental syncytiotrophoblast (STB). Although the role of these …

The syncytiotrophoblast of the human placenta is an epithelial barrier that interacts with
maternal blood and is a key for the transfer of nutrients and other solutes to the developing …

A proteomics screen of human placental microvillous syncytiotrophoblasts (STBs) revealed
the expression of dysferlin (DYSF), a plasma membrane repair protein associated with …

The multinucleated syncytial trophoblast, which forms the outermost layer of the placenta
and serves multiple functions, is differentiated from and maintained by cytotrophoblast cell …

Fusion of cytotrophoblasts with the overlying syncytiotrophoblast is an integral step in
differentiation of the human placental villous trophoblast. Multiple factors, such as growth …

Recently, the expression of a human endogenous retrovirus HERV-FRD, able to encode a
fusogenic envelope protein (syncytin 2), has been observed in human placenta. The aim of …

The fusion of villous cytotrophoblasts into the multinucleated syncytiotrophoblast is critical
for the essential functions of the mammalian placenta. Using RNA‐Seq gene expression …

Dysferlin is mutated in a group of muscular dystrophies commonly referred to as
dysferlinopathies. It is highly expressed in skeletal muscle, where it is important for …

Background Integrins are transmembrane receptors that mediate cell–extracellular matrix
(ECM) and cell-cell adhesion and trophoblast cells undergo changes in integrin expression …