Association between arterial stiffness and variations in oestrogen-related genes

I Peter, A Kelley-Hedgepeth, GS Huggins… - Journal of human …, 2009 - nature.com
Increased arterial stiffness and wave reflection have been identified as cardiovascular
disease risk factors. In light of significant sex differences and the moderate heritability of …

Sex differences in the relationship between estrogen receptor alpha gene polymorphisms and arterial stiffness in older humans

K Hayashi, S Maeda, M Iemitsu, T Otsuki… - American journal of …, 2007 - academic.oup.com
Background: Increased arterial stiffness is an independent risk factor for cardiovascular
disease. The estrogen system (estrogen and estrogen receptor-α [ER-α]) has potent …

Relations of inflammatory biomarkers and common genetic variants with arterial stiffness and wave reflection

R Schnabel, MG Larson, J Dupuis, KL Lunetta… - …, 2008 - Am Heart Assoc
Inflammation causes vascular dysfunction and perpetuates proatherosclerotic processes.
We hypothesized that a broad panel of inflammatory biomarkers and single nucleotide …

The menopausal transition does not appear to accelerate age-related increases in arterial stiffness

SM O'Neill, J Liu, MF O'Rourke, SK Khoo - Climacteric, 2012 - Taylor & Francis
Objective Arterial stiffness is an independent marker of cardiovascular risk that increases
with age, hypertension, diabetes and hyperlipidemia, both for men and women (although …

Heritability and a genome-wide linkage scan for arterial stiffness, wave reflection, and mean arterial pressure: the Framingham Heart Study

GF Mitchell, AL DeStefano, MG Larson, EJ Benjamin… - Circulation, 2005 - Am Heart Assoc
Background—Arterial stiffness and mean arterial pressure variably contribute to systolic
hypertension and increased cardiovascular risk. However, few prior community-based …

The Association of Estrogen Receptor-β Gene Variation With Salt-Sensitive Blood Pressure

W Manosroi, JW Tan, CM Rariy, B Sun… - The Journal of …, 2017 - academic.oup.com
Context Hypertension in young women is uncommon compared with young men and older
women. Estrogen appears to protect most women against hypertension, with incidence …

Sex-dependent association of blood pressure with oestrogen receptor genes ERα and ERβ

JA Ellis, T Infantino, SB Harrap - Journal of hypertension, 2004 - journals.lww.com
Background There is mounting physiological evidence for an important role of the oestrogen
receptors, ERα and ERβ, in vasodilatation and the response to vascular injury. In addition …

Gender influence on metabolic syndrome's effects on arterial stiffness and pressure wave reflections in treated hypertensive subjects

AD Protogerou, J Blacher, E Aslangul, C Le Jeunne… - Atherosclerosis, 2007 - Elsevier
BACKGROUND: In hypertensive subjects, aortic stiffness, an independent predictor of
cardiovascular (CV) risk, measured from pulse wave velocity (PWV), contributes to enhance …

Arterial stiffness in postmenopausal women: determinants of pulse wave velocity

CEI Lebrun, YT van der Schouw, AAA Bak… - Journal of …, 2002 - journals.lww.com
Objective To investigate the degree and potential cardiovascular determinants of arterial
stiffness, assessed by aortic pulse wave velocity (PWV) measurements, and to relate arterial …

Association of cross-sectional and longitudinal change in arterial stiffness with gene expression in the Twins UK Cohort

M Cecelja, B Jiang, M Mangino, TD Spector… - …, 2016 - Am Heart Assoc
We investigated whether expression of genes previously implicated in arterial stiffening
associates with cross-sectional and longitudinal measures of arterial stiffness. Women from …