Human leucocyte antigen (HLA)‐DRB1* 1501 and other class II alleles influence
susceptibility to multiple sclerosis (MS), but their contribution if any to the clinical course of …

Susceptibility to multiple sclerosis (MS) has been consistently associated with the Human
Leukocyte Antigen (HLA)-DRB1⁎ 1501 genotype, however effects on disease severity and …

Background: Previous studies on the influence of HLA-DRB1 alleles on multiple sclerosis
(MS) susceptibility and clinical course have mostly employed the 2-point genotyping …

Variation in major histocompatibility complex genes on chromosome 6p21. 3, specifically the
human leukocyte antigen HLA-DR2 or DRB1* 1501-DQB1* 0602 extended haplotype …

Genetic susceptibility to multiple sclerosis (MS) has so far been strongly localized to the
MHC class II region encoding the alleles of the haplotype HLA-DRB1∗ 1501,-DQA1∗ 0102 …

The MHC region has been shown to contain a susceptibility locus for multiple sclerosis (MS).
While the strongest association to date has been between HLA-DRB1∗ 1501 and MS, the …

Genetic susceptibility to multiple sclerosis (MS) is associated with the MHC located on
chromosome 6p21. This signal maps primarily to a 1-Mb region encompassing the HLA …

BACKGROUND: The association between susceptibility to multiple sclerosis (MS) and HLA-
DRB1⁎ 15 has been reported in various European populations. OBJECTIVE: To investigate …

Background: HLA-DRB1* 1501 (DR15) and other HLA class II alleles increase the risk of
developing multiple sclerosis (MS). However, the contribution of genetic heterogeneity to the …

The purpose of this study was to clarify the association of HLA‐DRB1 and‐DPB1 alleles with
multiple sclerosis (MS) in Japanese, to determine whether optico‐spinal MS (OS‐MS) and …