Diversity of sesquiterpene synthases in the basidiomycete Coprinus cinereus
S Agger, F Lopez‐Gallego… - Molecular …, 2009 - Wiley Online Library
Fungi are a rich source of bioactive secondary metabolites, and mushroom‐forming fungi
(Agaricomycetes) are especially known for the synthesis of numerous bioactive and often …
(Agaricomycetes) are especially known for the synthesis of numerous bioactive and often …
Agrocybe aegerita Serves As a Gateway for Identifying Sesquiterpene Biosynthetic Enzymes in Higher Fungi
Terpenoids constitute a structurally diverse group of natural products with wide applications
in the pharmaceutical, nutritional, flavor and fragrance industries. Fungi are known to …
in the pharmaceutical, nutritional, flavor and fragrance industries. Fungi are known to …
Insight into metabolic diversity of the brown‐rot basidiomycete Postia placenta responsible for sesquiterpene biosynthesis: semi‐comprehensive screening of …
H Ichinose, T Kitaoka - Microbial biotechnology, 2018 - Wiley Online Library
A wide variety of sesquiterpenoids have been isolated from basidiomycetes, and their
bioactive properties have attracted significant attention in an effort to understand …
bioactive properties have attracted significant attention in an effort to understand …
Traversing the fungal terpenome
MB Quin, CM Flynn, C Schmidt-Dannert - Natural product reports, 2014 - pubs.rsc.org
Covering: 1965–2014 Fungi (Ascomycota and Basidiomycota) are prolific producers of
structurally diverse terpenoid compounds. Classes of terpenoids identified in fungi include …
structurally diverse terpenoid compounds. Classes of terpenoids identified in fungi include …
Selectivity of fungal sesquiterpene synthases: role of the active site's H-1α loop in catalysis
F López-Gallego, GT Wawrzyn… - Applied and …, 2010 - Am Soc Microbiol
Sesquiterpene synthases are responsible for the cyclization of farnesyl pyrophosphate into a
myriad of structurally diverse compounds with various biological activities. We examine here …
myriad of structurally diverse compounds with various biological activities. We examine here …
Mushroom hunting by using bioinformatics: application of a predictive framework facilitates the selective identification of sesquiterpene synthases in basidiomycota
MB Quin, CM Flynn, GT Wawrzyn, S Choudhary… - …, 2013 - Wiley Online Library
The Basidiomycota fungi represent a diverse source of natural products, particularly the
sesquiterpenoids. Recently, genome sequencing, genome mining, and the subsequent …
sesquiterpenoids. Recently, genome sequencing, genome mining, and the subsequent …
Three previously unrecognised classes of biosynthetic enzymes revealed during the production of xenovulene A
Xenovulene A is a complex fungal meroterpenoid, produced by the organism hitherto known
as Acremonium strictum IMI 501407, for which limited biosynthetic evidence exists. Here, we …
as Acremonium strictum IMI 501407, for which limited biosynthetic evidence exists. Here, we …
Discovery and characterization of terpenoid biosynthetic pathways of fungi
GT Wawrzyn, SE Bloch, C Schmidt-Dannert - Methods in enzymology, 2012 - Elsevier
Fungi produce a myriad of terpenoids with a broad range of biological activities, many of
which can be adapted to human use. This requires knowledge of the enzymes responsible …
which can be adapted to human use. This requires knowledge of the enzymes responsible …
Identification of Diterpene Biosynthetic Gene Clusters and Functional Analysis of Labdane-Related Diterpene Cyclases in Phomopsis amygdali
T Toyomasu, R Niida, H Kenmoku… - Bioscience …, 2008 - Taylor & Francis
Two diterpene biosynthesis gene clusters in the fusicoccin-producing fungus, Phomopsis
amygdali, were identified by genome walking from PaGGS1 and PaGGS4 which encode the …
amygdali, were identified by genome walking from PaGGS1 and PaGGS4 which encode the …
Heterologous expression of cytotoxic sesquiterpenoids from the medicinal mushroom Lignosus rhinocerotis in yeast
Background Genome mining facilitated by heterologous systems is an emerging approach
to access the chemical diversity encoded in basidiomycete genomes. In this study, three …
to access the chemical diversity encoded in basidiomycete genomes. In this study, three …