Background Wnt signalling regulates multiple aspects of brain development in vertebrate
embryos. A large number of Wnt s are expressed in the embryonic forebrain; however, it is …

Several lines of evidence suggest that Wnt genes play a critical role in regulating
development of the vertebrate embryo. To address the role that this family may play in the …

Wnt signals have been shown to be involved in multiple steps of vertebrate neural
patterning, yet the relative contributions of individual Wnts to the process of brain …

In neural development, several Wnt genes are expressed in the vertebrate diencephalon,
including the thalamus. However, roles of Wnt signaling in the thalamus during …

Wnt proteins form a family of highly conserved secreted molecules that are critical mediators
of cell-cell signaling during embryogenesis. Partial data on Wnt activity in different tissues …

In the developing vertebrate CNS, members of the Wnt gene family are characteristically
expressed at signaling centers that pattern adjacent parts of the neural tube. To identify …

Wnts are essential for a multitude of processes during embryonic development and adult
homeostasis. The molecular structure of the Wnt pathway is extremely complex, and it keeps …

Axial patterning of the embryonic brain requires a precise balance between canonical Wnt
signaling, which dorsalizes the nervous system, and Sonic hedgehog (Shh), which …

In the present work, the expression patterns of the Wnt antagonists of the Dickkopf (Dkk)
family were characterized in the developing mouse forebrain. In situ hybridisation on …

Background A fundamental requirement for development of diverse brain regions is the
function of local organizers at morphological boundaries. These organizers are restricted …