Estrogen receptor (ER)-mediated effects have been associated with the modulation of
myocardial hypertrophy in animal models and in humans, but the regulation of ER …

The functional interaction, or “cross-talk,” between estrogen receptor (ER) and the
proinflammatory transcription factor nuclear factor (NF)-κB demonstrated in vitro has been …

Functional interactions or cross-talk between ligand-activated nuclear receptors and the
proinflammatory transcription factor nuclear factor-κB (NF-κB) may play a major role in …

Cardiac fibrosis evolves from the cardiac hypertrophic state. In this respect, estrogen and
estrogen receptor beta (ERβ) inhibit the effects of cardiac hypertrophic peptides that also …

Physiological effects of estrogen on myocardium are mediated by two intracellular estrogen
receptors, ERα and ERβ, that regulate transcription of target genes through binding to …

Background—Estrogen receptor (ER)–mediated effects have been associated with the
modulation of myocardial hypertrophy in animal models and in humans, but ER expression …

Estrogen has diverse effects on inflammation and immune responses. That pregnancy is
associated with remission of some autoimmune diseases and exacerbation of others …

We have previously shown that the myocardium is a target tissue for estrogen. Here, we
have identified rapid non-nuclear estrogen effects on the expression of the early growth …

Abstract Development of cardiac fibrosis portends the transition and deterioration from
hypertrophy to dilation and heart failure. Here we examined how estrogen blocks this …

OBJECTIVES AND AIMS: Transcriptional effects of estrogens are primarily mediated by the
two nuclear estrogen receptors (ER), ERα and ERβ. Both receptors are present in the …