A comprehensive expression analysis of WNT signalling pathway genes during several
stages of chicken facial development was performed. Thirty genes were surveyed including …

Wingless-related proteins (WNTs) regulate extension of the central axis of the vertebrate
embryo (convergent extension) as well as morphogenesis of organs such as limbs and …

Cleft lip with or without cleft palate (CLP) is the most common craniofacial birth defect in
humans. Recently, mutations in the WNT3 and Wnt9b genes, encoding two members of the …

At early stages of development, the faces of vertebrate embryos look remarkably similar, yet
within a very short timeframe they adopt species-specific facial characteristics. What are the …

Wnt signaling is critical for proper development of the head and face in the mouse embryo,
playing important roles in various aspects of craniofacial development ranging from axis …

Mammals and birds have common embryological facial structures, and appear to employ the
same molecular genetic developmental toolkit. We utilized natural variation found in bird …

The vertebrate upper lip forms from initially freely projecting maxillary, medial nasal, and
lateral nasal prominences at the rostral and lateral boundaries of the primitive oral cavity …

Cleft lip with or without cleft palate (CLP) usually results from a failure of the medial nasal
prominences to fuse with the lateral and maxillary prominences. This failure inhibits facial …

The WNT family of proteins is composed of several members. In the present study we
isolated the full length chick Wnt-6 cDNA and analyzed its expression pattern by in situ …

The canonical Wnt/β-catenin pathway is an essential component of multiple developmental
processes. To investigate the role of this pathway in the ectoderm during facial …