Live attenuated influenza viruses containing NS1 truncations as vaccine candidates against H5N1 highly pathogenic avian influenza

J Steel, AC Lowen, L Pena, M Angel… - Journal of …, 2009 - Am Soc Microbiol
Due to the high mortality associated with recent, widely circulating strains of H5N1 influenza
virus in poultry, the recurring introduction of H5N1 viruses from birds to humans, and the …

[HTML][HTML] Preparation of a standardized, efficacious agricultural H5N3 vaccine by reverse genetics

M Liu, JM Wood, T Ellis, S Krauss, P Seiler, C Johnson… - Virology, 2003 - Elsevier
Options for the control of emerging and reemerging H5N1 influenza viruses include
improvements in biosecurity and the use of inactivated vaccines. Commercially available …

Protective efficacy of the H5 inactivated vaccine against different highly pathogenic H5N1 avian influenza viruses isolated in China and Vietnam

G Tian, X Zeng, Y Li, J Shi, H Chen - Avian diseases, 2010 - meridian.allenpress.com
An inactivated H5N1 avian influenza (AI) vaccine generated by reverse genetics and
containing the hemagglutinin and neuraminidase genes of the H5N1 A/goose/Guangdong/1 …

Evaluation of a genetically modified reassortant H5N1 influenza A virus vaccine candidate generated by plasmid-based reverse genetics

K Subbarao, H Chen, D Swayne, L Mingay, E Fodor… - Virology, 2003 - Elsevier
Avian influenza A H5N1 viruses similar to those that infected humans in Hong Kong in 1997
continue to circulate in waterfowl and have reemerged in poultry in the region, raising …

A new generation of modified live-attenuated avian influenza viruses using a two-strategy combination as potential vaccine candidates

H Song, GR Nieto, DR Perez - Journal of virology, 2007 - Am Soc Microbiol
In light of the recurrent outbreaks of low pathogenic avian influenza (LPAI) and highly
pathogenic avian influenza (HPAI), there is a pressing need for the development of vaccines …

Strategies for developing vaccines against H5N1 influenza A viruses

T Horimoto, Y Kawaoka - Trends in molecular medicine, 2006 - cell.com
Recent outbreaks of highly pathogenic avian influenza A virus (H5N1 subtype) infections in
poultry and humans (through direct contact with infected birds) have raised concerns that a …

Protection of mice against lethal infection with highly pathogenic H7N7 influenza A virus by using a recombinant low-pathogenicity vaccine strain

E de Wit, VJ Munster, MIJ Spronken… - Journal of …, 2005 - Am Soc Microbiol
In 2003, an outbreak of highly pathogenic avian influenza occurred in the Netherlands. The
avian H7N7 virus causing the outbreak was also detected in 88 humans suffering from …

A consensus–hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses

MW Chen, TJR Cheng, Y Huang… - Proceedings of the …, 2008 - National Acad Sciences
H5N1 influenza viruses have spread extensively among wild birds and domestic poultry.
Cross-species transmission of these viruses to humans has been documented in over 380 …

The NS1 gene contributes to the virulence of H5N1 avian influenza viruses

Z Li, Y Jiang, P Jiao, A Wang, F Zhao, G Tian… - Journal of …, 2006 - Am Soc Microbiol
In the present study, we explored the genetic basis underlying the virulence and host range
of two H5N1 influenza viruses in chickens. A/goose/Guangdong/1/96 (GS/GD/1/96) is a …

Generation of live attenuated novel influenza virus A/California/7/09 (H1N1) vaccines with high yield in embryonated chicken eggs

Z Chen, W Wang, H Zhou, AL Suguitan Jr… - Journal of …, 2010 - Am Soc Microbiol
Several live attenuated influenza virus A/California/7/09 (H1N1)(CA09) candidate vaccine
variants that possess the hemagglutinin (HA) and neuraminidase (NA) gene segments from …