Placental proteomics: a shortcut to biological insight

JM Robinson, DD Vandré, WE Ackerman IV - Placenta, 2009 - Elsevier
Proteomics analysis of biological samples has the potential to identify novel protein
expression patterns and/or changes in protein expression patterns in different …

Proteomics of the human placenta: promises and realities

JM Robinson, WE Ackerman IV, DA Kniss, T Takizawa… - Placenta, 2008 - Elsevier
Proteomics is an area of study that sets as its ultimate goal the global analysis of all of the
proteins expressed in a biological system of interest. However, technical limitations currently …

Proteomics of the amniotic fluid in assessment of the placenta. Relevance for preterm birth

IA Buhimschi, CS Buhimschi - Placenta, 2008 - Elsevier
Proteomics is the study of expressed proteins and has emerged as a complement to
genomic research. The major advantage of proteomics over DNA–RNA based technologies …

Proteomic profiling reveals sub proteomes of the human placenta

WE Heywood, RL Preece, J Pryce, J Hallqvist… - Placenta, 2017 - Elsevier
Proteomic characterisation of the placenta has largely been focused on effect of disease,
anatomical features or specific cell types. We describe an unbiased proteomic mapping …

Novel “omics” approach for study of low-abundance, low-molecular-weight components of a complex biological tissue: regional differences between chorionic and …

K Kedia, CA Nichols, CD Thulin, SW Graves - Analytical and bioanalytical …, 2015 - Springer
Tissue proteomics has relied heavily on two-dimensional gel electrophoresis, for protein
separation and quantification, then single protein isolation, trypsin digestion, and mass …

Proteome profiling of human placenta reveals developmental stage-dependent alterations in protein signature

S Khorami Sarvestani, S Shojaeian, N Vanaki… - Clinical Proteomics, 2021 - Springer
Introduction Placenta is a complex organ that plays a significant role in the maintenance of
pregnancy health. It is a dynamic organ that undergoes dramatic changes in growth and …

A proteomic profile of the healthy human placenta

S Manna, J Scheel, A Noone, CJ McElwain, C Scaife… - Clinical Proteomics, 2023 - Springer
Background The placenta remains one of the least studied organs within the human body.
Yet, placental dysfunction has been associated with various pregnancy complications …

An initial proteomic analysis of human preterm labor: placental membranes

RH Butt, MWY Lee, SA Pirshahid… - Journal of proteome …, 2006 - ACS Publications
Human preterm labor (PL) is the single most significant problem in modern Obstetrics and
Gynecology, affecting∼ 10% of pregnancies worldwide, constituting the leading cause of …

Proteome analysis of human placentae: pre-eclampsia versus normal pregnancy

K Mine, A Katayama, T Matsumura, T Nishino… - Placenta, 2007 - Elsevier
Although placental proteins play multiple roles in fetal and placental development and in the
maintenance of pregnancy, many remain inadequately characterized. In the present study …

Placenta-derived proteins across gestation in healthy pregnancies—a novel approach to assess placental function?

MHL Degnes, AC Westerberg, M Zucknick, TL Powell… - BMC medicine, 2022 - Springer
Background Placenta-derived proteins in the systemic maternal circulation are suggested as
potential biomarkers for placental function. However, the identity and longitudinal patterns of …