[HTML][HTML] Common genetic variation and performance on standardized cognitive tests
ET Cirulli, D Kasperavičiūtė, DK Attix… - European Journal of …, 2010 - nature.com
One surprising feature of the recently completed waves of genome-wide association studies
is the limited impact of common genetic variation in individually detectable polymorphisms …
is the limited impact of common genetic variation in individually detectable polymorphisms …
Abnormal glycosylation of EAAT1 and EAAT2 in prefrontal cortex of elderly patients with schizophrenia
D Bauer, V Haroutunian, JH Meador-Woodruff… - Schizophrenia …, 2010 - Elsevier
The excitatory amino acid transporters (EAATs) are a family of molecules that are essential
for regulation of synaptic glutamate levels. The EAATs may also be regulated by N …
for regulation of synaptic glutamate levels. The EAATs may also be regulated by N …
DNA fluorocode: A single molecule, optical map of DNA with nanometre resolution
RK Neely, P Dedecker, J Hotta, G Urbanavičiūtė… - Chemical …, 2010 - pubs.rsc.org
We present a new method for single-molecule optical DNA mapping using an exceptionally
dense, yet sequence-specific coverage of DNA with a fluorescent probe. The method …
dense, yet sequence-specific coverage of DNA with a fluorescent probe. The method …
Association study of 182 candidate genes in anorexia nervosa
AP Pinheiro, CM Bulik, LM Thornton… - American Journal of …, 2010 - Wiley Online Library
We performed association studies with 5,151 SNPs that were judged as likely candidate
genetic variations conferring susceptibility to anorexia nervosa (AN) based on location …
genetic variations conferring susceptibility to anorexia nervosa (AN) based on location …
[HTML][HTML] Phenotypic consequences of copy number variation: insights from Smith-Magenis and Potocki-Lupski syndrome mouse models
G Ricard, J Molina, J Chrast, W Gu, N Gheldof… - PLoS …, 2010 - journals.plos.org
A large fraction of genome variation between individuals is comprised of submicroscopic
copy number variation of genomic DNA segments. We assessed the relative contribution of …
copy number variation of genomic DNA segments. We assessed the relative contribution of …
The genetic basis of thought disorder and language and communication disturbances in schizophrenia
DL Levy, MJ Coleman, H Sung, F Ji, S Matthysse… - Journal of …, 2010 - Elsevier
Thought disorder as well as language and communication disturbances are associated with
schizophrenia and are over-represented in clinically unaffected relatives of schizophrenics …
schizophrenia and are over-represented in clinically unaffected relatives of schizophrenics …
Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-Selective N-Methyl-d-aspartate Receptor Antagonists
We describe a new class of subunit-selective antagonists of N-methyl d-aspartate (NMDA)-
selective ionotropic glutamate receptors that contain the (E)-3-phenyl-2-styrylquinazolin-4 (3 …
selective ionotropic glutamate receptors that contain the (E)-3-phenyl-2-styrylquinazolin-4 (3 …
Association of common copy number variants at the glutathione S-transferase genes and rare novel genomic changes with schizophrenia
B Rodríguez-Santiago, A Brunet, B Sobrino… - Molecular …, 2010 - nature.com
Copy number variants (CNVs) are a substantial source of human genetic diversity,
influencing the variable susceptibility to multifactorial disorders. Schizophrenia is a complex …
influencing the variable susceptibility to multifactorial disorders. Schizophrenia is a complex …
SMARCA2 and other genome-wide supported schizophrenia-associated genes: regulation by REST/NRSF, network organization and primate-specific evolution
Y Loe-Mie, AM Lepagnol-Bestel… - Human molecular …, 2010 - academic.oup.com
The SMARCA2 gene, which encodes BRM in the SWI/SNF chromatin-remodeling complex,
was recently identified as being associated with schizophrenia (SZ) in a genome-wide …
was recently identified as being associated with schizophrenia (SZ) in a genome-wide …
Genome‐Wide Findings in Schizophrenia and the Role of Gene–Environment Interplay
R Van Winkel, G Esquivel, G Kenis… - CNS neuroscience & …, 2010 - Wiley Online Library
The recent advent of genome‐wide mass‐marker technology has resulted in renewed
optimism to unravel the genetic architecture of psychotic disorders. Genome‐wide …
optimism to unravel the genetic architecture of psychotic disorders. Genome‐wide …