Synthesis and transport of creatine in the CNS: importance for cerebral functions
E Béard, O Braissant - Journal of neurochemistry, 2010 - Wiley Online Library
J. Neurochem.(2010) 115, 297–313. Abstract Apart of its well known function of 'energetic
buffer'through the creatine/phosphocreatine/creatine kinase system allowing the …
buffer'through the creatine/phosphocreatine/creatine kinase system allowing the …
Mitochondria as a target in treatment
MC Frantz, P Wipf - Environmental and molecular mutagenesis, 2010 - Wiley Online Library
Mitochondria are key organelles that perform essential cellular functions and play pivotal
roles in cell death and survival signaling. Hence, they represent an attractive target for drugs …
roles in cell death and survival signaling. Hence, they represent an attractive target for drugs …
Functional improvement of focal cerebral ischemia injury by subdural transplantation of induced pluripotent stem cells with fibrin glue
SJ Chen, CM Chang, SK Tsai, YL Chang… - Stem cells and …, 2010 - liebertpub.com
Ischemic stroke is the leading cause of disability in the world. Cell transplantation has
emerged in various neurological diseases as a potential therapeutic approach in the …
emerged in various neurological diseases as a potential therapeutic approach in the …
Early C-reactive protein in the prediction of long-term outcomes after acute coronary syndromes: a meta-analysis of longitudinal studies
L He, X Tang, W Ling, W Chen, Y Chen - Heart, 2010 - heart.bmj.com
Objective To assess the overall effects by a meta-analysis. Data sources Electronic searches
on PubMed and Ovid Medline from their start to October 2009 were carried out. Objective …
on PubMed and Ovid Medline from their start to October 2009 were carried out. Objective …
Neuroprotection by ketamine: a review of the experimental and clinical evidence
JA Hudetz, PS Pagel - Journal of cardiothoracic and vascular …, 2010 - jcvaonline.com
NEUROPROTECTION MAY BE DEFINED AS the “pre-vention or amelioration of neuronal
damage evidenced by abnormalities in cerebral metabolism, histopathology or neurologic …
damage evidenced by abnormalities in cerebral metabolism, histopathology or neurologic …
Therapeutic hypothermia for acute ischemic stroke: ready to start large randomized trials?
HB Van Der Worp, MR Macleod… - Journal of Cerebral …, 2010 - journals.sagepub.com
Therapeutic hypothermia is a means of neuroprotection well established in the management
of acute ischemic brain injuries such as anoxic encephalopathy after cardiac arrest and …
of acute ischemic brain injuries such as anoxic encephalopathy after cardiac arrest and …
Hypoxia in high glucose followed by reoxygenation in normal glucose reduces the viability of cortical astrocytes through increased permeability of connexin 43 …
Brain ischemia causes more extensive injury in hyperglycemic than normoglycemic
subjects, and the increased damage is to astroglia as well as neurons. In the present work …
subjects, and the increased damage is to astroglia as well as neurons. In the present work …
Ubiquitin C‐terminal hydrolase‐L1 as a biomarker for ischemic and traumatic brain injury in rats
MC Liu, L Akinyi, D Scharf, J Mo… - European Journal of …, 2010 - Wiley Online Library
Ubiquitin C‐terminal hydrolase‐L1 (UCH‐L1), also called neuronal‐specific protein gene
product 9.5, is a highly abundant protein in the neuronal cell body and has been identified …
product 9.5, is a highly abundant protein in the neuronal cell body and has been identified …
Acute pathophysiological processes after ischaemic and traumatic brain injury
A Kunz, U Dirnagl, P Mergenthaler - Best practice & research Clinical …, 2010 - Elsevier
Ischaemic stroke and brain trauma are among the leading causes of mortality and long-term
disability in the western world. Enormous endeavours have been made to elucidate the …
disability in the western world. Enormous endeavours have been made to elucidate the …
Recurrent spontaneous spreading depolarizations facilitate acute dendritic injury in the ischemic penumbra
Spontaneous spreading depolarizations (SDs) occur in the penumbra surrounding ischemic
core. These SDs, often referred to as peri-infarct depolarizations, cause vasoconstriction and …
core. These SDs, often referred to as peri-infarct depolarizations, cause vasoconstriction and …