J. Neurochem.(2010) 115, 297–313. Abstract Apart of its well known function of 'energetic
buffer'through the creatine/phosphocreatine/creatine kinase system allowing the …

Mitochondria are key organelles that perform essential cellular functions and play pivotal
roles in cell death and survival signaling. Hence, they represent an attractive target for drugs …

Ischemic stroke is the leading cause of disability in the world. Cell transplantation has
emerged in various neurological diseases as a potential therapeutic approach in the …

Objective To assess the overall effects by a meta-analysis. Data sources Electronic searches
on PubMed and Ovid Medline from their start to October 2009 were carried out. Objective …

NEUROPROTECTION MAY BE DEFINED AS the “pre-vention or amelioration of neuronal
damage evidenced by abnormalities in cerebral metabolism, histopathology or neurologic …

Therapeutic hypothermia is a means of neuroprotection well established in the management
of acute ischemic brain injuries such as anoxic encephalopathy after cardiac arrest and …

Brain ischemia causes more extensive injury in hyperglycemic than normoglycemic
subjects, and the increased damage is to astroglia as well as neurons. In the present work …

Ubiquitin C‐terminal hydrolase‐L1 (UCH‐L1), also called neuronal‐specific protein gene
product 9.5, is a highly abundant protein in the neuronal cell body and has been identified …

Ischaemic stroke and brain trauma are among the leading causes of mortality and long-term
disability in the western world. Enormous endeavours have been made to elucidate the …

Spontaneous spreading depolarizations (SDs) occur in the penumbra surrounding ischemic
core. These SDs, often referred to as peri-infarct depolarizations, cause vasoconstriction and …