CD169+ macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes

P Barral, P Polzella, A Bruckbauer, N Van Rooijen… - Nature …, 2010 - nature.com
Invariant natural killer T cells (i NKT cells) are involved in the host defense against microbial
infection. Although it is known that i NKT cells recognize glycolipids presented by CD1d …

Invariant natural killer T cells recognize lipid self antigen induced by microbial danger signals

PJ Brennan, RVV Tatituri, M Brigl, EY Kim, A Tuli… - Nature …, 2011 - nature.com
Invariant natural killer T cells (i NKT cells) have a prominent role during infection and other
inflammatory processes, and these cells can be activated through their T cell antigen …

How invariant natural killer T cells respond to infection by recognizing microbial or endogenous lipid antigens

M Brigl, MB Brenner - Seminars in immunology, 2010 - Elsevier
Invariant natural killer T (iNKT) cells have evolved to recognize CD1d-presented lipid
antigens and are known to play important roles during infection with bacterial, viral …

Innate-like recognition of microbes by invariant natural killer T cells

M Kronenberg, Y Kinjo - Current opinion in immunology, 2009 - Elsevier
Invariant natural killer T cells (iNKT cells) express a restricted T cell antigen receptor (TCR)
repertoire and they respond rapidly to glycolipid antigens presented by CD1d. These …

CD1d-restricted iNKT cells, the 'Swiss-Army knife'of the immune system

JL Matsuda, T Mallevaey, J Scott-Browne… - Current opinion in …, 2008 - Elsevier
Natural Killer T cells are a distinct lymphocyte lineage that regulates a broad range of
immune responses. NKT cells recognize glycolipids presented by the non-classical MHC …

NKT cells: T lymphocytes with innate effector functions

L Van Kaer - Current opinion in immunology, 2007 - Elsevier
Natural killer T (NKT) cells are innate-like T lymphocytes that recognize glycolipid antigens
in the context of the MHC class I-related glycoprotein CD1d. Recent studies have identified …

The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansion

MT Wilson, C Johansson… - Proceedings of the …, 2003 - National Acad Sciences
CD1d-restricted natural killer T (NKT) cells are a subset of regulatory T cells that react with
glycolipid antigens. Although preclinical studies have effectively targeted NKT cells for …

Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs

RVV Tatituri, GFM Watts, V Bhowruth… - Proceedings of the …, 2013 - National Acad Sciences
CD1d-restricted natural killer T (NKT) cells include two major subgroups. The most widely
studied are Vα14Jα18+ invariant NKT (iNKT) cells that recognize the prototypical α …

[HTML][HTML] The response of CD1d-restricted invariant NKT cells to microbial pathogens and their products

L Van Kaer, VV Parekh, L Wu - Frontiers in immunology, 2015 - frontiersin.org
Invariant natural killer T (iNKT) cells become activated during a wide variety of infections.
This includes organisms lacking cognate CD1d-binding glycolipid antigens recognized by …

[HTML][HTML] Invariant NKT cells facilitate cytotoxic T-cell activation via direct recognition of CD1d on T cells

Y Qin, S Oh, S Lim, JH Shin, MS Yoon… - Experimental & molecular …, 2019 - nature.com
Invariant natural killer T (iNKT) cells are a major subset of NKT cells that recognize foreign
and endogenous lipid antigens presented by CD1d. Although iNKT cells are …