[HTML][HTML] Ionic and substrate mechanisms of atrial fibrillation: rotors and the excitation frequency approach

O Berenfeld - Archivos de cardiología de México, 2010 - scielo.org.mx
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in humans, however
its mechanisms are poorly understood and its therapy is often sub–optimal. This article …

Structural and functional bases of cardiac fibrillation: differences and similarities between atria and ventricles

D Filgueiras-Rama, J Jalife - JACC: Clinical Electrophysiology, 2016 - jacc.org
Evidence accumulated over the last 25 years suggests that, whether in atria or ventricles,
fibrillation may be explained by the self-organization of the cardiac electrical activity into …

Electrophysiological basis of atrial fibrillation

JR Ehrlich, S Nattel - Innovative management of atrial fibrillation, 2005 - Wiley Online Library
This chapter deals with the individual structural, functional and ionic bases of atrial
fibrillation (AF) under various clinical conditions. We focus on factors that may play a role in …

Mechanisms of atrial fibrillation: rotors, ionic determinants, and excitation frequency

O Berenfeld, J Jalife - Heart failure clinics, 2016 - heartfailure.theclinics.com
Atrial fibrillation (AF) is associated with increased morbidity and mortality in patients with
cardiovascular disease and its prevalence in the general population continues to increase. 1 …

A biophysical model of atrial fibrillation and electrograms: formulation, validation and applications

V Jacquemet - 2004 - infoscience.epfl.ch
Atrial arrhythmias are the most frequent rhythm disorders in humans and often lead to
severe complications such as heart failure and stroke. While different mapping techniques …

Electrophysiological properties of the fibrillating atrium: implications for therapy

HF Tse, CP Lau - Clinical and experimental pharmacology and …, 1998 - Wiley Online Library
Atrial fibrillation (AF) is the most commonly occurring cardiac dysrhythmia and remains a
challenge to medical therapy. Although the disorder has been recognized for over 100 …

Electrophysiological characteristics of permanent atrial fibrillation: insights from research models of cardiac remodeling

AM Climent, MS Guillem, F Atienza… - Expert review of …, 2015 - Taylor & Francis
Atrial fibrillation (AF) results in a remodeling of the electrical and structural characteristics of
the cardiac tissue which dramatically reduces the efficacy of pharmacological and catheter …

Pathophysiology of atrial fibrillation: From initiation to maintenance

M Yamazaki, J Jalife - Journal of Arrhythmia, 2012 - jstage.jst.go.jp
abstract Atrial fibrillation (AF) is the most common arrhythmia in adults; it affects
approximately 0.8 million patients in Japan alone. Yet despite many years of basic and …

Ablation of rotor domains effectively modulates dynamics of human: long-standing persistent atrial fibrillation

D Calvo, J Rubín, D Pérez, C Morís - Circulation: Arrhythmia and …, 2017 - Am Heart Assoc
Background: In human long-standing persistent atrial fibrillation, rotors potentially explain
atrial fibrillation maintenance, but their ablation remains controversial. We aimed to explore …

Atrial metabolism and tissue perfusion as determinants of electrical and structural remodelling in atrial fibrillation

D Opacic, KA van Bragt, HM Nasrallah… - Cardiovascular …, 2016 - academic.oup.com
Atrial fibrillation (AF) is the most common tachyarrhythmia in clinical practice. Over decades
of research, a vast amount of knowledge has been gathered about the causes and …