Cells typically respond quickly to stress, altering their metabolism to compensate. In
mammalian cells, stress signaling usually leads to either cell-cycle arrest or apoptosis …

The nucleolus is a prominent subnuclear compartment, where ribosome biosynthesis takes
place. Recently, the nucleolus has gained attention for its novel role in the regulation of …

Besides the canonical function in ribosome biogenesis, there have been significant recent
advances towards the fascinating roles of the nucleolus in stress response, cell destiny …

Once thought a mere ribosome factory, the nucleolus has been viewed in recent years as an
extremely sensitive gauge of diverse cellular stresses. Emerging concepts in nucleolar …

All organisms sense and respond to conditions that stress their homeostaticmechanisms.
Here we review current studies showing that the nucleolus, long regardedas a mere …

The nucleolus is a large nuclear membraneless organelle responsible for ribosome
biogenesis. Ribosomes are cytoplasmic macromolecular complexes comprising RNA and …

This review summarizes the current understanding of the role of nuclear bodies in regulating
gene expression. The compartmentalization of cellular processes, such as ribosome …

The nucleolus is a sub-nuclear body known primarily for its role in ribosome biogenesis.
Increased number and/or size of nucleoli have historically been used by pathologists as a …

The nucleolus is a nuclear organelle that coordinates rRNA transcription and ribosome
subunit biogenesis. Recent proteomic analyses have shown that the nucleolus contains …

The nucleolus is the largest and most studied nuclear body, but its role in nuclear function is
far from being comprehensively understood. Much work on the nucleolus has focused on its …